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Ligandrol (LGD-4033)

Let’s delve into the details of Ligandrol (LGD-4033), a selective androgen receptor modulator (SARM) that has gained attention in the fitness community. Here’s a comprehensive overview:

Ligandrol Mechanism of Action

Ligandrol selectively binds to androgen receptors in bones and muscles.

Unlike anabolic steroids, it doesn’t convert into estrogen and doesn’t significantly affect the liver or kidneys.

By activating these receptors, Ligandrol promotes muscle growth, increases strength, and enhances athletic performance.

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Main Benefits

Ligandrol (LGD-4033) offers several benefits to bodybuilders. Let’s explore them in detail:

Muscle Mass

In clinical trials, LGD-4033 has shown significant increases in lean muscle mass.

Even with a short cycle and small dosage, users gained approximately 1.21 kg (2.67 lbs) of muscle.

Muscular Strength

Users experience improved leg press strength and power, even without specific training.

Strength gains on LGD-4033 are often exceptional, even during calorie deficits.

Fat Loss

LGD-4033 can help reduce body fat in addition to promoting muscle growth.

It contributes to a leaner physique by preserving muscle while cutting.

Bone Density

Developed to treat osteoporosis, LGD-4033 leads to an improvement in bone mineral density.

Stronger bones are crucial for overall health and athletic performance.

Endurance and Recovery

LGD-4033 enhances endurance during workouts.

It aids in post-workout recovery, allowing for more frequent and intense training sessions.

Anabolic Effects

By binding to androgen receptors, Ligandrol triggers protein synthesis.

This creates an environment conducive to muscle growth.

Tissue Selectivity

Unlike anabolic steroids, LGD-4033 is tissue-selective.

It targets muscle and bone without causing androgenic effects in the prostate.

Positive Impact on Athletic Performance

LGD-4033’s effects on strength and muscle growth have led to its ban in professional sports by WADA.

Superior Strength Gains

Users often report adding significant weight to their squat or bench press 1RM after a cycle of LGD-4033.

Overall Athletic Performance

LGD-4033 contributes to enhanced athletic performance, making it valuable for bodybuilders and athletes.

Ligandrol Dosage

The typical cycle length is 6 to 10 weeks.

Dosage ranges vary, but most users take around 5 to 10 mg per day.

Always start with a lower dose and gradually increase if needed.

Remember that individual responses may vary, so consult a healthcare professional before starting any SARM.

Potential Side Effects

Ligandrol (LGD-4033), like any compound, may have side effects. Here are some potential ones to be aware of:


LGD-4033 can negatively impact HDL cholesterol levels, leading to a reduction of almost 40% in just 3 weeks at a dosage of 1 mg/day.

Testosterone Suppression

LGD-4033 may suppress testosterone production.

It’s essential to monitor hormone levels during and after a cycle.

Liver Toxicity

Although less severe than with steroids, LGD-4033 can still have an impact on the liver.

Regular liver function tests are advisable.

Water Retention and Gynecomastia

Some users report water retention and the development of gynecomastia (enlarged breast tissue).

Proper management and awareness are crucial.

Hair Loss

While not as common, some individuals may experience hair loss while using LGD-4033.

Other Possible Side Effects

Headaches and dry mouth are mild side effects.

Due to a lack of long-term safety data, other side effects cannot be ruled out.

When to Take It

Ligandrol is typically taken once a day.

Some users prefer morning dosing, while others split the dose between morning and evening.

Consistency matters; take it at the same time daily.

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Ligandrol Cycle

Here’s a comprehensive Ligandrol (LGD-4033) cycle guide tailored for beginners, intermediate users, and pro bodybuilders:

1. Beginners


  • Week 1-4: Start with a low dose of 5 mg/day.
  • Week 5-8: Increase to 10 mg/day.

Cycle Length

  • A beginner cycle typically lasts 8 weeks.

PCT (Post-Cycle Therapy)

  • After the cycle, consider a mild PCT using natural testosterone boosters like Tribulus terrestris or D-aspartic acid.


  • Regularly check testosterone levels and liver function.

2. Intermediate


  • Week 1-4: Begin with 10 mg/day.
  • Week 5-8: Increase to 15 mg/day.

Cycle Length

  • An intermediate cycle can extend up to 10 weeks.


  • A more robust PCT is recommended, including SERMs (Selective Estrogen Receptor Modulators) like Nolvadex (tamoxifen) or Clomid (clomiphene citrate).


  • Frequent blood tests to assess hormonal balance.

3. Pro Bodybuilders


  • Week 1-4: Start with 15 mg/day.
  • Week 5-8: Increase to 20 mg/day.

Cycle Length

  • Pro bodybuilders may extend the cycle up to 12 weeks.


  • A comprehensive PCT with SERMs and possibly HCG (human chorionic gonadotropin).


  • Rigorous monitoring of hormonal levels, liver enzymes, and overall health.


  • Always consult a healthcare professional before starting any SARM cycle.
  • Individual responses vary, so adjust dosages based on personal tolerance and goals.
  • Prioritize safety and health throughout the cycle.

What Are The Natural Alternatives to Ligandrol?


When seeking alternatives to Ligandrol (LGD-4033), it’s essential to prioritize natural supplements that align with your bodybuilding goals and prioritize safety. Here are some noteworthy natural alternatives you can consider:

Ostarine (MK-2866)

    • Known for its muscle-building and fat-burning properties.
    • Can be a suitable substitute for Ligandrol.
    • Helps preserve muscle mass during cutting phases.

Ligan 4033

    • A legal alternative to Ligandrol.
    • Mimics the effects of Ligandrol without harmful side effects.
    • Boosts muscle growth, strength, and endurance.
    • Prevents muscle cramps and aids post-workout recovery.

RadBulk and LigaBulk

    • Breakthrough creations by Brutal Force.
    • Safe and natural SARM alternatives.
    • Provide body-sculpting results.

Click here to buy Ligandrol (LGD4033) by Biaxol

Legality of Ligandrol

Let’s delve into the legality of Ligandrol (LGD-4033):

Investigational New Drug (IND)

    • In the United States, Ligandrol is classified as an Investigational New Drug (IND).
    • It means that it is not approved for any medical use by the FDA.
    • The FDA has clarified that LGD-4033 is not a legitimate dietary ingredient and should not be sold in supplements.

Black Market and Illegal Status

    • Despite its status as an IND, Ligandrol has been sold on the black market in countries where it is classified as an illegal substance.
    • Non-medical use of Ligandrol is not approved or regulated.

Clinical Development

    • Ligandrol was initially developed for the treatment of muscle atrophy in people with hip fractures.
    • It was also explored for cachexia, hypogonadism, and osteoporosis, but development for these indications was discontinued.
    • Preliminary clinical trials have shown improvements in lean body mass and muscle strength, but it is still under development and not approved for medical use.

Side Effects and Unknown Masculinization Potential

    • Possible side effects of Ligandrol include headache, dry mouth, lipid changes, decreased HDL cholesterol levels, and liver toxicity.
    • The potential for masculinization (such as virilization) is largely uncharacterized and unknown.

Legal Status Summary

    • Not approved for medical use.
    • Illegal to sell as a dietary supplement in the U.S.
    • Black market availability in some countries.

Buying Ligandrol Online

When it comes to purchasing Ligandrol (LGD-4033), it’s essential to prioritize safety, quality, and legality. Here are some reputable online options where you can find Ligandrol and other bodybuilding supplements:

Brutal Force Ligabulk

Best Overall: Known for its high-quality SARMs, including Ligandrol.

Offers genuine products and reliable customer service.

Crazy Bulk Ligan 4033 Ligandrol Alternative

Best Overall (Runner-Up): Crazy Bulk is a well-established brand in the bodybuilding industry.

Their Ligan 4033 alternative provides similar benefits to Ligandrol without the legal risks.

Brutal Force Ironbound SARMs Bulking Stack

Best for Muscle Gain: If you’re looking for muscle growth, consider this stack.

It combines various SARMs, including Ligandrol, for optimal results.

Etalaze has been a trusted steroid store since 2008.

They offer a range of bodybuilding gear, including Ligandrol alternatives.


As a valued SARM, bodybuilders can't resist Ligandrol's ability to promote lean muscle mass and strength gains without the water retention or bloating associated with traditional steroids. LGD-4033 selectively targets androgen receptors in muscle and bone tissue, leading to accelerated muscle growth and improved bone density.

However, its long-term effects and safety profile are still being studied, and it may come with potential side effects such as testosterone suppression and liver toxicity. As with any performance-enhancing substance, it's important to use LGD-4033 responsibly and under the guidance of your trainer or physician.

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