Steroids
The Extreme of Oral Steroids
History in Oral Steroids and The Underground Medicine
Let's start with the underground, as most people have to deal with. First, let's deal with the problems, which are counterfeits and fakes. The most faked oral steroids you will ever get are Primo, Halotestin, Cheque Drops, Anavar, and Turinabol. Dbol is almost always Dbol; Winstrol is very distinctly Winstrol. You’ll know when it's real; it has unique hardening properties. Also, your joints will likely feel like it's real Winstrol. If your jointing feels great and lubricates, you can be pretty much certain it is not Winstrol. So be careful where you get you're Primo, Halo, Cheques, Anavar, and Tbol.
Must Read: 6 Ways to Verify If a Steroid Is Fake
Anadrol:
Anadrol is surprisingly faked very little, but yes, it is faked. Occasionally, some things will be swapped instead of being fake, meaning underdosed or not contain the active ingredient. You may get a similar drug instead. Let's start with the most common trick that's pulled: the winning and Anavar switch.
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Anavar:
Anavar is expensive so you’ll probably get Winstrol instead of Anavar a good way to tell is via the joints side effect as both are relatively water-free drugs that promote strength really well. Winstrol puts more size on though but is significantly harsher on the lipids. But Anavar is the only steroid that supposedly doesn't close growth plates prematurely.
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I say ‘’supposedly’’ as I can't quite recall the entire study, but it was the most suitable steroid for a beginner out of any steroid I’ve ever seen. I’d have it tested if you were female as if it turns out to be Dbol or Winstrol, you will have possibly irreversible side effects, but if you got the real thing, you're good to go.
Primo and Anavar and low dose eq are suited for females. For the adventurous ones, low dose tren is handled surprisingly well but is only recommended for those who want to take their physique to the next level. Like everything, start low and play it by ear.
I’ve seen quite feminine women up to 300mg a week of tren, but anything more and you get bad sides. Most women will be able to grow and get leaner on 50-100mg of tren a week. Tren Hex is the best as it has the longest ester. Approved for human use in France.
Must Read: Best Anabolic Steroids For Women
Dianabol:
Dianabol was once given to housewives, and Halotestin was supposedly for clinical dwarfism once upon a time. Dbol kills some people's appetite, but its prescription purpose was to increase appetite in some people. The best drugs for bodybuilding use are going to be anabolic and tissue-building in nature that have androgenic and masculinizing characteristics you can live with.
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Must Read: What Kind of Gains to Expect on Halotestin Steroid Cycles?
This is a trade-off you have to personally decide for yourself. Top of the list when it comes to bodybuilding drugs is Primobolan and Tren, both have oral alternatives, but none are as good as the injectables. The only fan of Primo Acetate I know of was Mike Mentzer.
Now Dbol was the second oral steroid to my knowledge after methyl test, but Dbol is a surprisingly well-tolerated oral, and in Dr.Robert Kerr M.D’s book, he had met a powerlifter who took 7500mg a day of it for short periods, I assume, and he only began having side effects such as blood in the urine after some time.
Oral Steroids Proprieties
I know an NPC Competitor, former, not current, who was doing a bottle of Ciba Dbol a day for his entire 12-week preps, and he's nearly 60 now and fine health-wise. Every steroid has side effects, some more than others, but you can never assume or state that everyone will get all or even some of them. Some people do, but some don't.
I don't encourage high doses I encourage whatever dose is required to get the job done, it happening to be high is really only relative to what the goal is and individual tolerance. If the goal is the maximum size, the typical bulking oral Anadrol actually won't be that effective for that purpose Dbol will be; Anavar is exceptional for strength in high doses. Peter Grymkowski has admitted to doing 750mg of Anavar a day year-round and upping it to 1250mg 3 weeks out of the competition.
So that's 3 old school bottles a day, 2.5mg tabs 100 to a bottle. Side effects are overblown, but they have to be stated because they absolutely can occur; you can't ignore the fact that anyone doing over 400mg of any oral will likely be a person or should be a person who doesn't drink or smoke and takes liver, kidney, cholesterol/lipid, and heart health supplements and prostate meds if they are prone to it, do not take DHT’s if you're prone to hair loss, taking a DHT blocker will render DHT steroids less efficacious so don't bother.
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Oral Steroids Extremes
You can also have hawthorn berry at 2-3g a day to better support you're health and heart blood pressure on cycle. NAC is also a must when on high-dose orals. Peter Grymkowski and I believe that drinking lots of cranberry juice helps with the kidney, bladder, prostate, and minor liver support, and we have both been okay despite our high oral doses.
Oral steroids are Not all the same some are okay to push the boundaries, with some having a line you don't cross, Cheque drops Halotestin, and possibly even Superdrol. But primo and Anavar are very well tolerated by most people; Dbol moderately Anadrol is hit or miss. Some people tolerate it, some do not. Dbol was used by some Mr. America year-round in doses of 30-50mg.
This should show you how most of these steroids aren't as toxic as they seem, IF AND IT'S A BIG IF you're responsible for mitigating side effects. You can't drink on Halotestin, for example, or you are inviting liver failure.
I’ve heard of a story told by a famous Westside Barbell Legend, a powerlifter. For those who don’t know, also for those who don’t know Westside has the world's best powerlifters training there. He said he was with a friend who will remain nameless and downed 15 Anadrol in a sitting with his beer.
Now, this is the worst way to take steroids, and he was still okay. Provided it was for short enough periods, the drinks were very limited if not eliminated for the most part. My definition of fine means no liver failure and no side effects that are seriously life-threatening. A bit of water retention and no hunger aren't anything to worry about.
Proviron
Having no appetite is not an indicator of liver stress as other oral steroids are metabolized by the liver and you're hunger is at normal levels or elevated. Proviron is not methylated and with most non-methylated steroids, you need not fear overdosing them high, although you wouldn't really get anything out of Proviron other than sex drive and a bit of hardness/vascularity, all of which master Di-Propionate or Propionate can give to you better.
Winstrol:
Visually the best oral is Winstrol, but it destroys the joints for most people, which data won't fix, it will hide. Water in the joints and some minor smoothing of joint problems don't fix the actual problem, so either live with it and work around it or don't use oral Winstrol.
It produces a kind of hardness and separation that only tren provides, but Tren has more side effects. It's basically a toss-up between being a headcase or being more prone to injury via no fluid in the joints, and they're just grinning at each other.
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Glutamine:
I’ve never gotten the side effect, but those who mix Anadrol and Halo sometimes get a sex drive and erection that can become painful in very few cases. It's had to be drained of blood. Yes, their penis is being drained of blood. Halo also makes you even angrier than Anadrol does. So do not combine it with tren unless you want to be arrested. But it is done as it's super effective.
Some oral steroids have synergy some don't. Tbol and Winstrol have some synergy. Dbol and Anadrol have synergy. Anavar and Winstrol have synergy. Dbol and Tbol don't have synergy. Winstrol and Anadrol have minor synergy. Anavar and Tbol have some synergy.
Halotestin and Anadrol have almost too much synergy to the point you just become a lunatic. Gain so much strength you're at serious, serious risk of injuring yourself. Most side effects can be mitigated, although the hunger side effects, either increased or decreased, cannot be mitigated. Water retention and blood pressure and cholesterol can.
RBC
It can't, but if you remove your Own blood, technically, you can mitigate the side, but if you have tattoos or use steroids, you shouldn't be a candidate for blood donations. If you're smart, you can bloodlet properly if you don't know how do a lower dose. Take blood pressure aids when on compounds that affect the blood pressure. Pharm grade vs. underground can't compare, so don't try.
An underground steroid will always be exactly the same as pharm grade or underdosed, and more often than not it will be slightly underdosed and sometimes plainly cut. Yes, steroids are being cut. Usually, this is not an immediate health concern it's wasted. Maybe they tend to cut with the body's most abundant amino acid.
Glutamine! This isn't unheard of, considering iv amino acids were prominent in the ’60s and ’70s and then dried out a fair bit before the age of the internet. You likely won't notice any benefits. If you do obtain fake gear, all you can do is find another source, but it can be batch specific.
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Primobolan Tabs:
The ultimate test is ALWAYS the Primobolan test. I’d put my money on any lab that has real primo so that the rest of their stuff is good to go. Most labs will probably have decent everything but primo, which means when you finally get good primo, you know you’ve struck gold with your labor dealer. Why Primo? Well, it’s because it's rare and expensive. Oral Primo, especially that, 's even rarer than legit Halotestin.
Which is notoriously expensive. You will never find a bottle of real Halotestin under 120usd even if the tabs are only 5mg. So sometimes can determine by price alone. Dbol is heap so if that's bunk, the whole lab had to instantly disregard it.
Even if you're not an extreme oral user if you wish to be extremely cautious, my tips are simple and are the following: 2-3g of Hawthorn Berry via capsules or put it into your teabags NAC 2-2.5g oral or 1-1.5g Injectable Cranberry juice usually one small carton works, and that's a liter so about a quarter gallon (which I’d use to wash down the orals usually) Tudca was but isn't really necessary, Milk Thistle also but is way too mild (NAC in injectable form is the preferred method and used in hospitals in this manner for overdoses it is safe it is merely an amino acid they IV it but to extend t half-life over the one day a subcue injection is best although an intramuscular do the injection may be most comfortable)
In medical studies, the main issues arise from blood pressure and liver functions. The thing is, none of these people tested while taking liver, kidney, heart, blood pressure or lipid support which helps lower or eliminate these side effects, but I can't ignore they exist, but I can say they, for the most part, can avoid them.
Personal Experience:
My personal experience with orals is pretty simple, but as it relates to this article. I will share the most extreme examples, none of which will recommend. 1500mg of Dianabol on the day of a meet and 500mg daily to the meet starting from 6 weeks out.
Dbol
I’ve had one man admit to 1000mg of Dbol a day for 3 weeks before a meet, and he’s one of the greatest squatters the world has ever seen. I notice the higher dosages result in less water weight and more strength. Dbol at 500mg resulted in quite a little water, but it begins to round out the muscles and stimulate the CNS significantly.
Must Read: The Trenbolone Dianabol Stack to Build Mass and Strength
I’ve used up to 600mg a day because I had heard Steve Michalik had done it. So I tried it for a short period, only a few weeks, and I was perfectly fine actually, I didn't gain any water at all I got vascular and very strong on it. I have run Turinabol for 20 weeks and gained a lean 30 lbs.
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But I was using 140-200mg daily of it split into two doses. I believe, like Anavar, it is an oral that should run at lower doses for longer periods, unlike other orals, which are better for kickstarting or ending cycles. Turinabol is a funny steroid because it's known for really increasing sexual appetite, a side effect I hated; if combined with something like test and tren, then you probably need to pay attention to it.
I maintained my appetite on my experience with Dbol and Tbol but not Anadrol. I believe that Anadrol is better to use for pre-contest than for the offseason. Once you control the water weight, you can remain full on it. Which I was.
Conclusion
I’d say the water retention seems to be a lot less in doses above 300mg when it comes to Dbol. 600mg and above for Anadrol and Tbol should have minimal water.
The most enjoyable oral steroids are Tbol and Anavar. Pumps aren't a bad thing to me. That's a very minor side effect in my life if I cramp. I am so pumped I have to lean on someone's letterbox I find it funny. It means what I’m on works; I’ve gotten away with just using potassium from nu-salt. I have taurine but never had to use it. I occasionally use it post-workout as I enjoy intense contractions and pumps; using it pre-workout may disrupt that.
Side Effects of Oral Steroids:
| High Blood Pressure | Tension headaches | Stomach upset | Jaundice |
| .Blood in Urine | Benign Hepatic tumors | Adrenal Fatigue | Loss of appetite |
| Decreased Sex Drive | Cramping | Water retention | Nose Bleeds |
| In rare cases Priapism | Nausea | Joint Pain | Depression in some cases |
| Gynecomastia | Prostate Enlargement | Insomnia | Insomnia |
| Hair loss | Acne | Body hair Growth | Voice Deepening |
| Clitoral Enlargement | Testicular Shrinkage | Loss of regular periods | Aggression |
| Confidence | Masculinization in women | Feminization in men | Oily Skin |
| Dry Skin | Increase in bad cholesterol | The decrease in good Cholesterol | High Hematocrit |
| Thickening of the left | ventricular wall of the heart | Sleepiness and Lethargy |
Bodybuilding
Is Training/Lifting Barefoot A Good Idea? Find Out
For decades, the gym floor has echoed with the thud of cushioned sneakers, lifting shoes, and high‑tech trainers promising better stability, more power, and improved performance. Yet in recent years, a surprising shift has taken hold among serious lifters: many are kicking off their footwear entirely. What began as a fringe practice—often dismissed as quirky or unsafe—has evolved into a growing movement embraced by bodybuilders, powerlifters, and functional fitness athletes who swear that training barefoot unlocks a deeper, more natural kind of strength.
At first glance, the idea seems almost counterintuitive. After all, modern athletic shoes are engineered with layers of support, padding, and structure. But that’s exactly the point. As lifters push for better technique, stronger lifts, and more efficient movement patterns, many are realizing that all that cushioning may be doing more harm than good. By removing the barrier between foot and floor, barefoot training forces the body to engage stabilizing muscles that shoes often mute. The result? A stronger foundation, improved balance, and a more connected kinetic chain from the ground up.
Beyond performance, the barefoot trend taps into a broader shift toward natural movement and functional strength. Lifters are rediscovering the importance of foot mechanics—how the toes grip, how the arches support, and how the ankles align. These subtle details influence everything from squat depth to deadlift power. And as more athletes experiment with barefoot sessions, they’re finding that the benefits extend far beyond the feet themselves.
Of course, going shoeless in the gym isn’t just about following a trend. It’s about rethinking how we build strength, questioning long‑held assumptions, and exploring what happens when we strip training back to its most primal form. Serious lifters aren’t throwing away their shoes for style—they’re doing it for results.
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Advantages of Training Barefoot for Pro Bodybuilders
For professional bodybuilders, every detail matters—how the body moves, how muscles fire, and how efficiently force transfers through the kinetic chain. Training barefoot has emerged as a surprisingly effective way to refine these details and unlock performance benefits that shoes often mask.
One of the biggest advantages is enhanced stability. Without the interference of thick soles or elevated heels, the feet can spread naturally, creating a wider, more grounded base. This stability is crucial during heavy compound lifts like squats, deadlifts, and lunges, where even minor wobbling can compromise form or reduce power output. Barefoot training allows bodybuilders to feel the floor directly, improving balance and control under load.
Another major benefit is greater activation of stabilizing muscles, especially in the feet, ankles, and lower legs. Modern footwear often restricts natural movement, causing these smaller muscles to weaken over time. Training barefoot forces them to engage, strengthening the foundation that supports every lift. For bodybuilders, this translates to better joint integrity, improved symmetry, and reduced risk of chronic overuse injuries.
Barefoot lifting also enhances proprioception—the body’s ability to sense position and movement. With more sensory feedback from the ground, athletes can fine‑tune their technique, adjust their stance, and maintain optimal alignment throughout each rep. This heightened awareness can improve squat depth, deadlift mechanics, and overall lifting efficiency.
Must Read: The Proper Approach to Buying Steroids Online (updated)
Additionally, training without shoes encourages more natural biomechanics. The feet move freely, the arches function as intended, and the ankles maintain a neutral position. This can help correct imbalances caused by years of training in restrictive footwear, ultimately supporting better long‑term performance.
For pro bodybuilders chasing marginal gains, barefoot training offers a simple yet powerful way to build strength from the ground up—literally. It’s not just a trend; it’s a strategic tool for maximizing muscle engagement, improving technique, and enhancing overall athletic longevity.
Possible Downsides of Lifting Barefoot
While barefoot training has gained popularity among casual lifters for its “natural” feel and improved ground contact, the situation is very different for professional bodybuilders. At elite levels, athletes handle extreme loads that demand maximum stability, protection, and performance efficiency. Without proper footwear, the risks multiply — from injuries and reduced leverage to hygiene concerns and long-term joint stress. The following points highlight why barefoot lifting can be problematic for pro bodybuilders.
1. Reduced Foot Protection
Bare feet leave you vulnerable to dropped weights, sharp objects, or heavy equipment. For pro bodybuilders handling massive loads, this risk is amplified.
2. Higher Risk of Injury
Without shoes, the bones, tendons, and ligaments in your feet absorb more stress. Heavy squats or deadlifts can easily cause sprains or fractures.
3. Lack of Arch Support
Shoes provide structural support that helps prevent issues like flat feet or plantar fasciitis. Barefoot lifting removes that safeguard.
4. Instability Under Heavy Loads
Gym floors can be slippery or uneven. Shoes add grip and stability, while barefoot training increases the chance of wobbling or losing balance.
Related Article: Muscle Density Decoded: Why Hardness Beats Size
5. Reduced Performance in Certain Lifts
Olympic lifts and squats often benefit from raised heels or firm soles. Barefoot training limits leverage and can reduce maximum output.
6. Increased Stress on Ankles and Knees
Without cushioning, impact forces travel directly into the joints. Over time, this can contribute to chronic pain or injury.
7. Hygiene Concerns
Gyms are breeding grounds for bacteria and fungi. Training barefoot raises the risk of infections like athlete’s foot.
8. Limited Leg Drive in Deadlifts
While barefoot deadlifting improves ground contact, it reduces leverage compared to specialized lifting shoes designed for maximum force transfer.
9. Not Competition-Ready
Most bodybuilding and powerlifting competitions require footwear. Barefoot training doesn’t translate well to actual performance standards.
10. Potential Long-Term Damage
Repeated barefoot lifting under heavy loads can cause chronic foot problems, misalignment, and reduced career longevity.
Overall
As we mentioned earlier, training barefoot has become a trend among some athletes, but for professional bodybuilders the practice carries both potential benefits and serious drawbacks. On the positive side, lifting without shoes can improve proprioception — the body’s awareness of movement and position — which may enhance balance and stability during certain exercises. Barefoot training also strengthens the small muscles of the feet and ankles, potentially reducing reliance on supportive footwear. For lifts like deadlifts, direct contact with the floor can improve force transfer and reduce unnecessary elevation caused by cushioned soles.
However, the disadvantages are far more significant at elite levels. Bare feet lack protection against dropped weights or sharp equipment, exposing bodybuilders to severe injury risks. Without arch support or cushioning, stress is shifted to the ankles, knees, and hips, increasing the likelihood of chronic pain or joint damage. Performance in squats and Olympic lifts often suffers, since specialized shoes provide leverage and stability that barefoot training cannot replicate. Hygiene is another concern, as gym floors harbor bacteria and fungi. Finally, barefoot lifting does not align with competition standards, where footwear is mandatory.
In short, while barefoot training offers some functional benefits, professional bodybuilders face greater risks that outweigh its advantages.
Anabolic Steroids
Using Insulin Needles to Inject AAS: Pros and Cons
Bodybuilding has long been associated with the pursuit of physical excellence, where athletes and enthusiasts dedicate themselves to sculpting muscular physiques. You need rigorous training, disciplined nutrition, and, in some cases, the use of performance-enhancing substances. Among these substances, anabolic-androgenic steroids (AAS) occupy a controversial space. While medically prescribed for specific conditions, AAS are often used to accelerate muscle growth, improve recovery, and enhance overall performance. Their use, however, is fraught with ethical, legal, and health-related concerns.
One practical issue that arises in this context is the method of administration. AAS are typically injected intramuscularly, requiring needles that can deliver oil-based solutions deep into muscle tissue. Yet, some individuals turn to insulin needles—originally designed for subcutaneous delivery of insulin—as an alternative. This choice is often motivated by the perception that insulin needles are less intimidating, less painful, and more discreet. For bodybuilders who may be inexperienced with injections, the appeal of a smaller, finer needle can be strong.
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However, the suitability of insulin needles for AAS administration is highly debated. While they may offer certain conveniences, their limitations in terms of depth, absorption, and compatibility with thicker solutions raise significant concerns. Misuse can lead to complications ranging from ineffective dosing to infections and tissue damage.
Must Read: Running and Bodybuilding: Is it a Good Idea to Mix Them?
In bodybuilding culture, where experimentation and peer influence often shape practices, understanding the pros and cons of using insulin needles for AAS injections is essential. By examining both benefits and the potential risks, we can better appreciate the complexities of AAS injection and emphasize the importance of informed, responsible decision-making.
Why Insulin Needles
Insulin needles are generally preferred for many types of injections because they are shorter, thinner, less painful, and reduce the risk of complications compared to larger needles
Patient comfort: Insulin needles are designed to minimize pain. Their fine gauge and short length make injections less intimidating and more tolerable, especially for people who need frequent injections.
Reduced risk of complications: Shorter needles lower the chance of hitting muscle or nerves when delivering medication subcutaneously. This reduces risks like bruising, bleeding, or accidental intramuscular injection
Effective delivery: For insulin and other subcutaneous medications, shorter needles are just as effective as longer ones. They ensure the drug reaches the correct tissue layer without unnecessary depth.
Ease of use: Their design makes them simple to handle, even for patients self-administering injections daily. This accessibility encourages adherence to treatment
Compatibility with subcutaneous injections: Many medications besides insulin—such as certain vaccines, hormones, and biologics—are delivered under the skin. Insulin needles are well-suited for these because they match the required depth and absorption rate.
Insulin Needles vs. Intramuscular Needles in Bodybuilding
When it comes to injecting anabolic-androgenic steroids (AAS), bodybuilders often weigh the choice between insulin needles and traditional intramuscular needles. Insulin needles are very fine and short, usually ranging from 29 to 31 gauge and only a few millimeters in length. This makes them far less intimidating and significantly less painful to use. For athletes who inject frequently, the reduced discomfort and minimal scarring are appealing, especially since visible bruising or scar tissue can detract from the aesthetic goals of bodybuilding. Their wide availability in pharmacies and association with legitimate medical use also adds to their convenience and discretion.
However, insulin needles are designed for subcutaneous injections, meaning they deposit medication just under the skin. AAS, on the other hand, are typically oil-based compounds that require intramuscular delivery for proper absorption. The fine bore of insulin needles makes drawing and injecting these thicker solutions difficult, and their short length often fails to reach muscle tissue. This mismatch can lead to poor absorption, underdosing, or even localized complications such as abscesses and tissue irritation.
Intramuscular needles, by contrast, are longer and thicker—usually 21 to 25 gauge and 25 to 40 millimeters in length. While they cause more pain and can be intimidating for beginners, they are specifically designed to deliver oil-based substances deep into muscle tissue. This ensures that AAS are absorbed effectively and reduces the risk of complications when used correctly. Over time, repeated intramuscular injections may cause bruising or scar tissue, but medically they remain the appropriate tool for this type of administration.
In short, you may prefer insulin needles for their comfort, accessibility, and cosmetic advantages, but intramuscular needles remain the medically suitable option for AAS injections. The perceived safety of insulin needles does not outweigh the risks of improper delivery, making the choice more about convenience than effectiveness.
Downsides of Using Insulin Needles for AAS in Bodybuilding
For bodybuilders, the downsides of insulin needles in AAS use are significant: poor absorption, infection risk, tissue damage, and wasted product. While they may reduce pain and appear more convenient, they compromise both safety and effectiveness. In bodybuilding culture, where results are paramount, these drawbacks make insulin needles a risky and counterproductive choice.
Improper absorption
Insulin needles are designed for subcutaneous injections, but AAS typically require intramuscular delivery. Injecting into fat or shallow tissue can lead to poor absorption, reduced effectiveness, and unpredictable results.
Also See: Fitness Lessons from A Navy Seal’s Training Routine
Viscosity mismatch
AAS solutions are often oil-based and much thicker than insulin. Fine-gauge insulin needles struggle to draw and push these solutions, leading to blocked syringes, incomplete injections, or excessive force that damages tissue.
Risk of infection and abscesses
Because oil may pool in subcutaneous tissue instead of dispersing into muscle, it can irritate the area and create a breeding ground for bacteria. This raises the risk of painful abscesses that may require medical intervention.
Underdosing and wasted product
If the steroid doesn’t reach the muscle, the bodybuilder may not achieve the intended anabolic effect. This not only wastes expensive compounds but also tempts users to increase frequency or dosage, compounding health risks.
Tissue damage
Repeated shallow injections can cause lumps, irritation, or necrosis in fatty tissue. For bodybuilders focused on aesthetics, visible damage under the skin undermines their goals.
False sense of safety
Many athletes assume insulin needles are “safer” because they are smaller and widely used in diabetes care. In reality, this perception can mask the fact that they are medically inappropriate for AAS, leading to dangerous practices.
Related Article: Best Syringes for Steroid Injection on Amazon
Overall
Bodybuilders and athletes often face difficult choices when it comes to performance enhancement, and the method of administering anabolic-androgenic steroids (AAS) is one of them. Insulin needles, with their fine gauge and short length, are attractive because they reduce pain, minimize scarring, and are easy to obtain. For individuals who inject frequently, these qualities can seem like practical advantages.
However, the reality is that insulin needles are not designed for oil-based compounds that require intramuscular delivery. Their short length and narrow bore make them unsuitable for reaching muscle tissue, leading to poor absorption, underdosing, and potential tissue irritation. The risk of infection or abscess formation is also heightened when AAS are deposited into fatty tissue rather than muscle. What may appear to be a safer, more comfortable option can ultimately compromise both health and performance outcomes.
Athletes who prioritize long-term progress must recognize that convenience should never outweigh safety. While insulin needles may seem appealing, they are not always appropriate for AAS administration. The discipline that defines bodybuilding and athletic success should extend to responsible decision-making, ensuring that choices made in pursuit of strength and aesthetics do not undermine overall well-being.
Anabolic Steroids
Is NAD+ The Best Anti-aging Molecule for Men Over 40?
NAD+(Nicotinamide Adenine Dinucleotide) has become the quiet obsession of athletes and bodybuilders who care as much about longevity as they do about performance. For men over 40, the game changes: recovery slows, energy dips, and the margin for error—sleep, nutrition, stress—gets razor-thin. That’s where NAD+ steps in. As a central coenzyme in cellular metabolism, NAD+ powers the mitochondria that generate ATP, supports DNA repair, and helps regulate inflammation and oxidative stress—the exact pressures that compound with age and intense training. The catch? NAD+ levels decline as we get older, and that drop doesn’t just feel like “getting tired”; it shows up as reduced work capacity, stubborn recovery, and a harder fight to preserve lean mass.
For the seasoned lifter, anti-aging isn’t about turning back the clock—it’s about staying dangerous: maintaining strength, clarity, and resilience year after year. By supporting NAD+—through smart training, lifestyle, and targeted precursors like NR or NMN—you’re not chasing a miracle; you’re reinforcing the cellular systems that keep you strong. Think steadier energy across sets, cleaner recovery between sessions, and a more robust response to stressors that typically erode performance after 40.
This article explores how NAD+ intersects with muscle metabolism, hormonal signaling, and recovery pathways, and what practical steps can help you sustain the physique and output you’ve built. If you’re a man over 40 who refuses to age passively, NAD+ isn’t hype—it’s a lever worth understanding and pulling with intention.
Must Read: How to Manage Joint Stiffness While on AAS
Why NAD+ Levels Drop in Men Over 40
NAD+ levels decline with age because the body’s ability to produce and preserve this vital coenzyme weakens, while demand for it increases.
Reduced biosynthesis: The enzymes and pathways that create NAD+ from precursors like niacin and tryptophan become less efficient over time.
Increased consumption: NAD+ is used by repair enzymes such as PARPs (for DNA repair) and sirtuins (for regulating metabolism and aging). As DNA damage and oxidative stress accumulate with age, these enzymes consume more NAD+, depleting reserves.
Greater degradation: Another enzyme, CD38, becomes more active with age. CD38 breaks down NAD+, and its rising activity is strongly linked to age-related decline in NAD+.
Mitochondrial dysfunction: Aging cells often suffer from less efficient mitochondria. Since NAD+ is central to mitochondrial energy production, dysfunction accelerates its depletion.
Lifestyle and stress factors: Poor sleep, chronic stress, alcohol, and high-intensity training without proper recovery can further drain NAD+ levels, especially in men over 40
Why This Matters for Men Over 40
- Lower NAD+ means slower recovery, reduced energy output, and greater susceptibility to inflammation.
- Declining NAD+ is linked to fatigue, cognitive decline, and accelerated aging.
For athletes and bodybuilders, this translates into harder muscle maintenance, longer recovery windows, and plateaus in performance.
Remedies to Boost NDA+ Levels in Men Over 40
Men and athletes over 40 can boost NAD+ levels through a mix of lifestyle strategies (exercise, fasting, sleep), dietary choices (niacin-rich foods), and supplementation (NR, NMN, NAD+ IV therapy).
Lifestyle Approaches
Regular exercise: Endurance and resistance training stimulate mitochondrial function and naturally increase NAD+.
Intermittent fasting: Periods of caloric restriction activate sirtuins, which depend on NAD+.
Quality sleep: Restorative sleep reduces oxidative stress and preserves NAD+ reserves.
Stress management: Chronic stress elevates NAD+ consumption; mindfulness and recovery practices help conserve it.
Avoid excess alcohol: Alcohol metabolism depletes NAD+, so moderation is key.
Related Article: Healing Peptides in Focus: BPC-157 vs TB-500 for Injury Recovery
Dietary Strategies
Niacin-rich foods: Chicken, tuna, salmon, turkey, and mushrooms provide vitamin B3, a precursor to NAD+.
Tryptophan sources: Eggs, dairy, and nuts support NAD+ synthesis via the kynurenine pathway.
Polyphenols: Resveratrol (found in grapes and red wine) activates sirtuins, indirectly supporting NAD+.
Ketogenic diet: Promotes fat metabolism and enhances NAD+/NADH ratio.
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Supplementation
Nicotinamide Riboside (NR): A direct precursor shown to raise NAD+ levels in humans.
Nicotinamide Mononucleotide (NMN): Another precursor with strong evidence for boosting NAD+ and supporting anti-aging pathways.
NAD+ IV therapy: Direct infusion used by some athletes for rapid replenishment.
Co-factors like magnesium and B vitamins: Support enzymatic reactions that sustain NAD+ metabolism.
Advanced/Medical Options
CD38 inhibitors: Experimental compounds that reduce NAD+ breakdown.
PARP inhibitors: Limit excessive NAD+ consumption during DNA repair (still under research).
Hormonal optimization: Testosterone and growth hormone balance indirectly support NAD+ pathways in men over 40.
The Catch:
Energy & endurance: Higher NAD+ means more efficient ATP production.
Recovery & repair: Supports DNA repair and reduces inflammation after training.
Anti-aging resilience: Helps maintain muscle mass, cognitive clarity, and metabolic health.
NAD+ Delivery Methods
1. Intravenous (IV) NAD+ Therapy
- Direct infusion of NAD+ into the bloodstream.
- Used in clinics for rapid replenishment of cellular NAD+.
- Often promoted for anti-aging, recovery, and cognitive clarity.
- Sessions can last several hours, as NAD+ must be infused slowly to avoid side effects (like nausea or flushing).
Dosing: Typically ranges from 250 mg to 1000 mg per session, but exact protocols vary by clinic and medical supervision.
2. Intramuscular or Subcutaneous Injections
- Less common than IV, but some practitioners use NAD+ injections for quicker delivery than oral supplements.
- Provides a shorter, more concentrated boost compared to IV drip.
- Still requires medical oversight, as NAD+ injections can be uncomfortable and must be dosed carefully.
Oral Supplementation
1. NAD+ Precursors (NMN & NR)
- Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR) are widely available as capsules or powders.
- These compounds are converted into NAD+ inside cells.
- Easier, safer, and more practical for long-term use compared to IV therapy.
Dosing: Common ranges are 250–500 mg daily, though some studies explore higher doses.
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2. NAD+ Capsules
- Direct oral NAD+ supplements exist, but absorption is less efficient than precursors.
- Most experts recommend NMN or NR instead, as they are better studied and more bioavailable.
Overall
In the pursuit of strength, endurance, and longevity, NAD+ emerges as more than just a biochemical cofactor—it is a cornerstone of vitality for athletes and men over 40. As natural levels decline with age, the consequences ripple through energy, recovery, and resilience. By embracing lifestyle strategies, nutrient-rich diets, and modern supplementation, bodybuilders can sustain performance while slowing the clock on cellular aging. Whether through daily NMN or NR, or targeted therapies under medical guidance, supporting NAD+ is an investment in both present power and future health—a path to staying strong, sharp, and ageless in the decades ahead.
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