What Are The Stages of Topical Steroids Withdrawal?
What are Steroids?
Steroids are the hormones the human adrenal cortex produces. They also refer to the synthetic drug with cortisol effects. Steroids, also known as corticosteroids, are very different from steroid compounds used by athletes to enhance their performances. Usually used in medical cases. Medical conditions steroids used to treat include allergies, asthma, dermatitis, hives, Addison's disease, Crohn’s disease, leukemia, prostate cancer, etc.
Steroids are classified into types depending on the effect they create within the body. They also produce many side effects, such as depression, anxiety, insomnia, hypertension, fluid retention, muscle wasting, decreased height, cataracts, glaucoma, peptic ulceration, and TSW (topical steroids withdrawal).
Must Read:: Can Blocking Cortisol Lead to Steroid-Like Muscle Gains?
These are medications in creams, lotions, ointments, solutions, serums, gels, sprays, foam, oils, shampoos, and other substances made for the skin or scalp. Also used for anti-inflammatory purposes, to treat or control skin infections such as eczema and dermatitis. Other names for topical steroids are topical corticosteroids, glucocorticosteroids, and cortisone.
Effects of Topical Steroids:
These steroids cause the same effects as the corticosteroids produced by the adrenal glands above the kidneys. Other side effects of applying these steroids on the skin or scalp include narrowing blood vessels, suppression of immune response, and reduced cell turnover. All the effects of using these steroids can be classified under the following:
- Anti Inflammatory
The Potency of Topical Steroids:
The potency of topical steroids refers to the working capacity of the medication, and they can be grouped into four:
- Low Potency: Topical Steroids classified as having low potency include alclometasone dipropionate, hydrocortisone, and desonide.
- Moderate Potency: Topical Steroids with medium potency include betamethasone valerate, clocortolone pivalate, flurandrenolide, fluocinolone, fluticasone propionate, and hydrocortisone valerate.
- High Potency: Topical steroids grouped under this category include desoximetasone, halcinonide, amcinonide, and triamcinolone acetonide.
- Very High Potency: Topical steroids in this category include betamethasone dipropionate, diflorasone diacetate, fluocinonide, clobetasol propionate, and clobetasol propionate.
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The potency of a Topical Steroid would largely depend on the following factors:
- Formulating components
- The amount that reaches the target cells
- The specific molecule
- The rate of absorption through the skin.
You can purchase topical steroids with mild potency, just over pharmaceutical counters, but those with high and very high potency should only be on doctor’s prescriptions.
Conditions that would require being treated and controlled by the use of Topical Corticosteroids include:
- Eczema (atopic eczema): This skin condition causes the skin to feel itchy, scaly, dry, and cracked. It may even lead to severe skin inflammation. This inflammation causes the skin to become red, dark brown, or gray, depending on skin tone. It usually is a long-term condition that affects the central part of the skin, such as the hands, backs, knees, faces, scalps, etc. However, it can still be controlled and treated using topical steroids. It is the most common form of eczema.
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- Dandruff: This skin condition usually affects the scalp, making it dry and itchy. It causes white flakes on the scalp and hair. Using a shampoo containing topical corticosteroids should help in treating this skin condition.
- Psoriasis: This is a skin condition that usually occurs on the elbows, knees, scalp, legs, and lower back but can occur on any part of the body. It causes a small patch of red, flaky, crusty, and itchy skin. This chronic disease is caused by the multiplied production of skin cells resulting in a build-up. This skin condition can also be controlled by the use of topical steroids.
- Nappy Rash: This is a skin condition in babies that causes a sore and itchy red patch of skin on the baby’s bottom most. It can also happen in the form of spots or blisters. Using a cream containing topical steroids can help with this situation, especially when it is in its severe state.
This skin condition can occur in the mouth, groin, nails, and other body parts. It causes a cluster of glossy elevated colored blotch on the affected area. This area is usually sore, itchy, and red. Using a medication containing topical steroids can help with this condition.
- Discoid Lupus Erythematous: This condition causes skin rashes, extreme fatigue,, and inflammation of the joints. It can also lead to weight loss and extreme joint pain. This condition can be controlled by using creams that contain topical steroids.
- Skin Irritation: Skin irritation characterized by swollen, itchy, and red skin parts can be caused by many factors. An insect bite is a factor. Applying a medication that contains topical steroids would be effective in alleviating the pain.
Combination with Other products:
Topical steroids are usually used with other ingredients, such as anti-bacterial and anti-fungal, to create a more effective result. The risks involved in using topical steroids with other drugs are quite low, and there is no significant effect on the potency of topical steroids when combined with other products.
These other drugs do not affect the concentration or effect of topical steroids. However, it is strongly advised that other topical medications should not be carried out simultaneously as topical corticosteroids to avoid creating more adverse effects.
How Topical Corticosteroids Are Used:
If you purchase any topical steroid from over the pharmaceutical counter, ensure you follow the instructions on the leaflet. Otherwise, you should adhere strictly to the doctor’s prescription. These substances are often applied to the affected part once or twice daily for two weeks or more. It should be used less frequently as treatments commence. The use of these medications should be reduced to once a day to avoid the occurrence of topical steroid withdrawal.
Also, it should not be applied all over the body but to the affected parts. It should be applied gently to the skin. If you use emollients, avoid using both substances at the same time. Give a 30 minutes time difference between the applications of both substances. These emollients help to relieve skin irritation and dryness.
The Finger Print Unit
The fingerprint unit acts as a guide for using the right dosage of topical steroids in treating skin conditions. You squeeze a quantity of the product from the tip of your finger to the first crease. This quantity should be enough to treat skin conditions over a patch of your skin two times the size of your palm. However, the dosage will still depend on what is being treated and the part of the body it is being treated. This is major because some body parts have thinner skin layers and are hence more sensitive than others. This dosage is often referred to as FTUs(s).
The absorption of topical steroids into the body occurs in different ways. For instance, the greatest absorption happens through the skin layer of the genitals, eyelids, and creases. Hence, potent and highly potent topical steroids should not be used on these parts of the skin.
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The least absorption of topical steroids occurs through the skin layer of palms and soles. Hence, low and moderately potent topical steroids may seem ineffective when applied to these parts of the skin. Using bandages or wraps to occlude the affected part would also help to increase the absorption of topical steroids through the skin layer.
Below is the recommended dosage for each part of an adult's body, using the Finger Print Unit
- 0.5 FTU for the skin found around the genitals.
- 1 FTU for skin located around the hands, elbows, and knees.
- 1.5FTUs for the skin located around the feet, including the soles.
- 2.5 FTUs for skin located around the face and neck
- 3 FTUs for the skin located around the scalp
- 4 FTUs for the skin located around the hand, arm, and the buttocks
- 8 FTUs for the legs and chest or the legs and the back
Who should use Topical Corticosteroids?
Adults and children can use topical steroids. However, avoid using topical steroids for treatment if you have infected skin, broken skin, or skin conditions like acne and open sores. Pregnant and nursing mothers should only use topical steroids in necessary situations. Research shows that the prolonged use and abuse of these substances can cause defects in the unborn child.
Therefore, using topical steroids with high potency should not be practiced by nursing and breastfeeding mothers. There is no proof that the content can contact the breast milk mother. Apply all caution during usage, topical steroids, and even low potency. Do not apply topical steroids to a nursing mother’s breasts; if she must use these medications, she should also be careful to wash off the cream before breastfeeding her child. This safety measure is significant to prevent the child from being harmed.
Side effects of using Topical Steroid Withdrawal:
For the use of most medications, there are side effects that may occur with different individuals. These side effects should not be confused with Topical Steroid Withdrawal. The side effects include:
- Some individuals may experience specific internal side effects that are similar to the symptoms of crushing syndrome.
- It can also result in skin thinning, that is, the reduction of skin elasticity.
- Stretch marks in armpits or genitals.
- Tearing of the skin due to the extreme thinness of the skin layer.
- The enlargement of blood vessels.
- The thickness and increased length of hair.
- It can also lead to cataracts and glaucoma when used frequently over the eyelids.
- Stinging of the skin can also occur when topical steroids apply to areas of the skin that have inflammation or are broken.
- Topical steroids can also heighten the effects of other skin infections, such as herpes simplex.
Topical Steroid Withdrawal:
This is also known as red skin syndrome or steroid dermatitis, which occurs after a person ceases to use topical steroids after prolonged regular use or the abuse of topical steroids. This condition usually occurs with the use of topical steroids with high levels of potency. The symptoms are mostly on the face and genitals. However, there is no exact time or duration for these symptoms to appear. It differs in individuals; in some, it may be a few months, while for others, it could take many years. Individuals with atopic dermatitis and women who blush often are at more risk. Very few reports have occurred in children. The first known case of topical steroid withdrawal happened in 1979.
This condition is mainly caused by the abuse, prolonged or regular use of topical steroids for more than a year. It was once believed that the adrenal glands only produce cortisol. However, recent research has proven that keratinocytes in human skin should also be included in the list. The prolonged or regular use of topical steroids would cause an adverse expression on the surface of lymphocytes.
We mustn't attribute every skin condition to Topical Steroids Withdrawal. Some symptoms of Topical Steroid Withdrawal are redness and rash on the face, excluding the nose and around the lips. This rash usually begins from the part of the skin that initially had the condition to be treated. Redness of the arms except for the palms and fingers. The reduction of the skin's elasticity can also be a way to tell if you have this condition. A burning feeling under the skin also forms part of the diagnosis. The reddened part of the skin may not just be a patch. It may also appear as the original skin condition the topical steroid is applied to treat or control. Your skin can also feel thickened and swollen.
Using this product with the right frequency and dosage and over the appropriate duration helps treat and control skin conditions. Side effects and topical steroid withdrawal only occur when you use the product in larger quantities or frequently over a long period, beyond the prescriptions of doctors, dermatologists, and physicians. It is also important that the use of this treatment need to be under the supervision of a dermatologist.
Deciding not to use topical steroids to treat or control skin conditions due to the knowledge of these side effects and topical steroids withdrawal may not be the best of choices as these substances can prove effective in the treatment of skin conditions, mainly when used according to prescription and over the right duration. Besides, this condition is pretty rare both in adults and children.
Significant signs and symptoms of topical steroid withdrawal include:
- Spreading Dermatitis through the skin, usually starting from the location or region previously affected by the skin condition that creates.
- Skin Inflammation accompanied by a burning, stinging sensation.
- Redness of the skin, usually the face, excluding the nose and around the lips.
- Swelling of different regions of the skin. This particular symptom is one the affected individual should waste no time in informing the physician or dermatologist.
- Intense itching in various areas of the skin is also a sign or symptom.
- Increased skin sensitivity to other topical products or atmospheric conditions.
- Oozing of liquid substances from the different parts of the skin.
These symptoms may develop weeks or months after the stoppage of topical steroid withdrawal. It is usually different per individual, but most cases happen with individuals who have used the product for more than 12 months.
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These signs and symptoms can also be classified into two types. Both are referred to as erythema to edematous and papulopustular. The erythema to edematous type is found in individuals with atopic or seborrheic dermatitis, accompanied by swelling, burning, redness of the skin, and heightened skin sensitivity. All these symptoms would occur within a fortnight from the stoppage of topical steroids.
The papulopustular type is found in individuals who have used these medications to treat acne. This comes with symptoms such as pimples, nodules, and redness. This is when this product is for cosmetic purposes.
Prevention of Topical Steroids Withdrawal
The most effective prevention method is using these medications strictly based on prescriptions. These symptoms are more likely to appear in these medications that are misused. The more frequently topical steroids are used, the more likely the individual to develop topical steroids withdrawal. The more potent the topical steroid and if used for a longer period than prescribed, the higher the probability of having topical steroid withdrawal. Use topical steroids to treat or control skin conditions and not for cosmetic purposes. Preventing these withdrawal symptoms is simple if you adhere to the above guidelines. However, in totally preventing topical steroid withdrawal, treatment of chronic skin conditions with the use of topical steroids shouldn't avoid or discourage.
Treatment of Topical Steroid Withdrawal:
No one treatment widely agrees upon this. However, the first step would be to consult your dermatologist or skin care physician. There has to be a diagnosis to be sure that the symptoms noticed are of topical steroid withdrawal and not another skin condition like eczema.
Once the diagnosis has been made, the next step would be to stop the wrong use of these medications. There have been some arguments about stopping these medications' use abruptly or gradually. However, there is no significant difference in the results produced by both actions. It highly advises stopping the use of the medications immediately.
Support and psychological care should also be patient. Other ways to help with the condition include using ice compresses, systemic doxycycline, tetracycline or calcineurin inhibitors. Ointments and balms such as shea butter have also be found to be helpful during this time. Epsom salt bath is also helpful in the recovery process. Antihistamines should be used to help with the intense itching of the skin that also occurs as a symptom. Immunosuppressants suggest helping as well.
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Another method would be to use oral steroids to reduce the symptoms. If it has led to secondary infections, oral antibiotics should be used. Patients should use soaps and detergents that would be suitable for sensitive skin. Also, wear clothes that are milder and softer on the skin to help reduce irritation. There have also been suggestions for natural and alternative medicine. However, these methods take approval from your doctor before attempting to use them so they do not worsen the condition.
Duration of Treatment:
The duration of treatment and recovery is not the same for everyone. However, it usually influences by the period through which these medications are used; the longer the period of use would mean a more extended period for recovery. The duration of recovery and the time it would take for the skin to return to normal would also depend on the treatment used. This duration can be months or even years for specific individuals. It advises taking steps to prevent this from occurring instead of waiting so long for your skin to return to normal.
In conclusion, topical steroids are very effective in controlling and treating skin conditions, both mild and chronic. It may lead to an eventual cure for some but for others, it may help relieve the symptoms. However, if used in excess, abused, used in large quantities and over a long period, it may lead to topical steroid withdrawal. Though this condition is quite rare, it advises that it prevents strictly following prescriptions. It would be good to also have your treatment monitored by your dermatologist or physician.
Top Drugs on WADA Watchlist Athletes Must Look Out For in 2022
To promote the integrity of sports, the World Ant-Doping Agency (WADA) has prohibited the manufacture, supply, and use of certain substances. These substances have been found to boost athletes' performance beyond their natural capabilities, thus disadvantaging other athletes who are not using the senses. Most of these drugs are hormone boosters and are readily available on the streets, where the public can have access at affordable prices.
The crackdown on illegal substances has driven most of its manufacturers out of the market by revoking their licenses or prosecution. However, some manufacturers and suppliers have found a way to beat the system and continue producing and supplying the substances under clandestine programs. Moreover, athletes are the biggest victims of their shady operations since doping not only ruins careers but also interferes with the athletes' long-term health.
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Regulatory bodies such as WADA have categorized prohibited substances using criteria such as chemical composition and severity of their effects. Additionally, there are banned methods WADA has outlined for athletes to avoid at all costs. Without further delay, here is the updated list of prohibited substances and procedures outlined on WADA's official website.
Anabolic Androgenic Steroids (AAS)
- 7-Keto DHEA
- Transforming growth factor-beta signaling inhibitors such as etanercept
- Innate repair receptor agonists such as EPO and CEPO
- Erythropoietin receptor agonists such as EPO and Depo.
- GITA inhibitors
- Hypoxia-Inducible factor activating agents such as cobalt and vaadaadugstat.
- Growth hormone-releasing factors such as GHRH, GHS, GHRPs, and Examorelin, among others.
Growth Factors and Modulators
- Fibroblast growth factors (FGFs)
- Platelet-derived growth hormone (PDGF)
- Insulin-like growth factor (IGF-1)
- Thymosin and its derivatives
- Hepatocyte growth factor (HGF)
- Vascular endothelial growth factor (VEGF)
- Mechano growth factor (MGF)
Note: There are exceptions to the use of Beta-2 agonists. For instance, inhaled salbutamol should not exceed 600 micrograms over eight hours starting from any dose. Additionally, inhaled formoterol, salmeterol, and vilanterol must not exceed 54, 200, and 25 micrograms, respectively, over 24 hours.
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Hormone and Metabolic Modulators
- Activin A-neutralizing antibodies
- Activin receptor IIB competitors
- Myostatin inhibitors such as myostatin binding proteins and antibodies
- Activators of the AMP-activated protein kinase
- Insulin and insulin-mimetics
Diuretic and Masking Agents
- Plasma expanders
- Etacrynic acid
WADA prohibits the manipulation of blood and blood components. t includes adding foreign red blood cells to the blood circulating in the body. It also prohibits athletes from introducing any form or quantity of homologous, autologous, and heterologous blood into their bodies. Athletes cannot boost oxygen delivery to specific body parts by artificially altering oxygen uptake and transportation. It is usually done by introducing modified hemoglobin products and other perfluorochemicals. However, they're allowed to boost oxygen uptake through inhalation. Finally, the regulatory body does not condone any intravascular manipulation of the blood and its components through chemical or physical means.
WADA collects samples from suspected cases regularly for analysis. In that case, athletes are prohibited from tampering with or manipulating the samples collected for analysis purposes. The control body has cited sample substitution and adulteration as their officers' most common tampering methods. Athletes can use specific chemicals for medical and other purposes other than performance enhancement. However, it forbids intravenous infusions or injections of less than 12 hours for doses above 12 ml.
Also, gene and cell doping is another malpractice among athletes that has drawn the attention of the sports watchdog. It has been found that some participants are using nucleic acid or its analogs to alter genome sequences, thus giving them added advantage when competing. They're advised to restrain themselves from gene editing, transfer, and silencing because it will inevitably put them on the wrong side of the law.
WADA has made it clear that it prohibits using all cannabinoids by athletes, whether synthetic or natural. That includes all substances contained in cannabis and its product. Additionally, products that contain some levels of THC or those that mimic it are prohibited in totality. Cannabidiol is the only cannabis-related substance that WADA has not banned.
- Triamcinolone acetonide
From the WADA list of prohibited substances and methods above, it is evident that most drugs we use every day are mentioned. However, it is essential to note that not all drugs are said to harm your body. For instance, cannabis and its products are mentioned, but we use it daily for medical and recreational purposes. WADA is only trying to create a level playing field for all athletes. That way, every win will be deserved, and a loss may not be contested by participants who feel cheated. Similarly, some substances are detrimental to your health and must be avoided at all costs, whether you're a competitive athlete or not.
Testosterone Propionate Cycles solo cycle
When it comes to bodybuilding, fat burning, and improvement in strength, testosterone propionate is the first name that comes into our mind. There are so many synthetic anabolic steroids in the market used by bodybuilders. Also, not all of them contain testosterone in an adequate amount. Testosterone compound is available for bodybuilders to improve endurance and performance. Irrespective of your favorite testosterone, ensure the base compound of your steroid cycle is testosterone. The reason is to improve the overall health benefits and reduce the health challenge that comes with the use of steroids as a bodybuilder. Everyone needs to take it seriously to avoid falling victim to health challenges—other side effects associated with using a steroid for sports and bodybuilding.
Testosterone Enanthate and Cypionate
Testosterone Enanthate and Cypionate have reduced the popularity of Propionate. These are the steroids available in the market today; known as “Performance Boosters”. There are many reasons athletes prefer Propionate over enanthate and Cypionate (a form of Testosterone compound). One of the reasons is that the Propionate intake results in lead to water reduction in the human body. It offers the same health benefits associated with the other two forms.
More so, many other features of the Propionate make it better and more preferable to the other two mentioned above. The first benefit of Propionate is that it offers users a better opportunity to increase their ability to maintain stability. Also, it increases hormonal blood levels due to frequent injections. To make you understand why Testosterone Propionate is better than other forms, it got FDA approval to treat diseases and other medical issues in men and women. Men with medical conditions get a solution from this compound. Female use of steroids is illegal in most countries of the world.
What is Test Propionate?
Testosterone comes in different forms, and you need to know the type you want to buy before involving your money. The testosterone propionate is popularly called “Test Pro” to bodybuilders and other people in the fitness world. More so, the Test Pro is a Testosterone esterified variant, and it is becoming more popular than other variants in the bodybuilding industry. The history of Test Pro dates back to 1935 when it comes to a bid to find out how to maximize Testosterone use. Schering AG is a pioneer marketer of the hormone in the US, and the hormone later became the most popular and widely used Testosterone form until the 1960s.
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More so, it is exciting for you to know that Test Pro has been released to sublingual forms, which was discontinued due to its lack of popularity. For some years back, Testosterone is among the three top and most popular steroids. Today, there are many other forms in the market to choose from when one wants to buy. Available in the injectable form, Testosterone is easy to take without much discomfort. These are the reasons one has to take advantage of the product to boost their performance in sports and other aerobic activities.
Related Article:: Why I like Testosterone Propionate More Than Enanthate and Cypionate?
The Truth You Should Know About Testosterone Propionate
Due to the many health benefits associated with Testosterone Propionate, it is approved by the FDA for men. The compound is available for men to improve their fitness and bodybuilding industry. So, more people prefer this compound for their bodybuilding benefits instead of other forms available in the market. The base of your steroid cycle should be exogenous testosterone. This propionate's importance cannot be overemphasized and is well known to experienced users.
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However, most new steroid users think they can continue to take steroids without the effect of the solo cycle. Some people also believe they do not need testosterone to manage the solo cycle. What newbie steroid users do not know is that trying to handle their solo circle without making use of testosterone has a dangerous effect on their health in the long run.
Facts about the Testosterone Solo Cycles
It is necessary to understand more about the cycles test for the P solo cycle of your Testosterone before taking it. It is the mistake most newbies make when it comes to using the compound. So, before you use Testosterone Propionate, you must figure out the Solo Cycles of the steroid and how to enhance its benefits to your health. As for the Testosterone Propionate, its cycles go from 8 – 10 weeks or within six weeks.
More so, do not forget to learn more about the kick-in period of the steroid before going for it, as that can determine the result you will get at the end of the day. There is a standard kick-in period for every steroid to the users. It is mainly within 2-4 weeks within the cycles. Your steroid use experience will determine your solo cycle. There is a dosage for those in the beginner and intermediate levels in the use of steroids. There is an opportunity for beginner and intermediate users to enjoy the Testosterone Propionate 10-week cycle to get the required result from the compound.
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The cycle is regarded as the lean mass or bulking cycle based on the expectation of the user. To get maximum steroid results, maintain a 300mg-500mg user cycle weekly. This cycle should continue until the 10th week. It is essential to be followed by the new steroid user to maintain good health and avoid unnecessary side effects that can impact one’s life. But for experienced steroid users, the recommended cycle for the first eight weeks is from 500mg to 700mg weekly.
Test Propionate Cycles Benefits You Should Know
Testosterone is a vital hormone in men that helps develop men's sex organs. It is a hormone associated with men, and its deficiency can result in different symptoms, such as a decrease in bone mass, erectile dysfunction, sex drive, and more. The functions of the hormone include:
- Muscles and bone development.
- Hair growth, deepening of the voice, and other physical appearance of men.
- Sperm production.
With these enormous benefits associated with testosterone, you can discover why its deficiency can spell doom to any man lacking it in the required quantity. However, the production of testosterone reduces with age, which makes older men often show the symptoms of low testosterone as they get older. Before discussing the benefits of Test Propionate cycles, it is necessary to look at the symptoms or signs of the low testosterone level in men. Some of these symptoms include:
- Hair loss.
- Erectile dysfunction.
- It reduced testicle size.
- Decrease in bone mass.
- Decrease in the amount of semen.
- Sleep difficulty.
- Decrease in muscle mass.
- We have reduced sex drive.
- Low energy level.
- Hot flashes.
- Sudden mood changes.
- High body fat.
The presence of these signs is not a good one, which is why the testosterone supplement of different types in pharmacies.
Treat testosterone deficiency, steroid is the right supplement for it. Adding to the fact that Testosterone Propionate helps users treat their deficiency in testosterone and also feel better about their bodies, the compound is beneficial to fitness enthusiasts, athletes, and bodybuilders. The Testosterone Propionate cycle will produce its users with many benefits.
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Some of these benefits you need to know include:
Improve Protein Synthesis
Protein synthesis helps improve muscle mass and ensure quicker recovery after each round of intense training. You need to understand the need for protein synthesis to know why you need the compound to help synthesize the protein in the body. It also stands as the main route for the disposal or removal of amino acids. The activation of the Amino acids is done by adhering to the particular molecules of RNA transfer and assembling using the ribosomes already specified through RNA messenger.
Improve Retention of Nitrogen
Another importantbenefit of the Test Prop Cycles is the increased rnitrogen retention The reduction of the nitrogen content of the body by the Testosterone Propionate is another benefit users stand to gain. It is the benefits that help to boost the available anabolic instead of the catabolic.
Boost the Production of Red Blood Cell
Red blood cell production is necessary for an increase in performance, endurance, and strength for athletes and bodybuilders. The Test Pro Cycles helps to boost the production of red blood cells to help the bodybuilders perform better. More so, the production of more red blood cells helps to allow the flow of more oxygen to the body, tissues, muscles, and other organs. That is essential in boosting performance and making long-distance runners cover more distance within a short time.
Glucocorticoid or Stress Hormone Inhibition
Stress hormones can be dangerous when allowed to grow out of range. It can result in depression and suicidal thoughts, which can be risky for human existence and health. One way to avoid allowing this thing to become a problem is through the intake of steroids. Testosterone propionate helps to inhibit stress hormone or glucocorticoid in the body. There are also oodles of inflammation-related molecules inhibited by Glucocorticoid. Some of them include Arachidonic acid metabolites, cytokines, chemokine’s, adhesion molecules, and more.
There are many other benefits associated with the use of Test P, which made it the best choice for both beginners and regular users. Knowing what you stand to gain from the use of steroids will make you ready to take it more and benefit from it as you desired. Some other benefits associated with the use of steroid include:
- It offers fast results and leaves the body quicker when compare to other esters.
- Is useful for muscle gains and cutting cycles.
- It is ideal for females and beginners in comparison to the slower esters.
What are the effects to expect when taking testosterone propionate?
Before going for the Testosterone Propionate, you should take time to research the possible effects to expect in your body. Make sure you understand the reason Test Pro has FDA approval and why many bodybuilders go for it before adopting it as part of your routine for bodybuilding. The truth is that Propionate works faster in the body of athletes compared to other users. Insulin levels and other growth factors increase with a single dose of the Propionate injection into the bloodstream. Some of the positive effects of this compound you need to know before adopting it include:
- Cleans the muscles in groups.
- Burn fats faster.
- Improve endurance.
- Boost strength for workout and recovering time.
- Boost sexual desire.
These are the results associated with the Testosterone Propionate that made it the best for bodybuilders. With a single injection of the hormone into the body, you will get improved performance as an athlete.
The Testosterone Propionate Cycle for Beginners
When you want to bulk up muscles, gain strength, and also improve your performance during the workout through the use of steroids, you must choose wisely. Testosterone propionate is the best steroids for beginners, professionals, and female bodybuilders. Do not go for the cycle without seeking the recommendation of the medical doctor. As a beginner, it is recommended that you take the ester only within an eight-week cycle at 100mg for two days.
Also, the minimum dosage for the beginner is 500mg per week and continues with it for the first ten weeks. The recommended minimum dosage will help to introduce the body with the steroid and ensure a balance between the side effects and the results. Adhering to the recommended dosage and cycle duration for a steroid is necessary as it will enable you to get the result you want without having issues with the side effect.
The Recommended Testosterone Propionate Cycle for Intermediate Users
Do not jump in to make use of steroids when you want to enhance your workout performance, build your muscle mass, and also increase your strength. The intermediate users can get the result they want when they start with a 10-week cycle. At the intermediate level of the steroid use is compound with some other compounds, such as Dianabol and Deca-Durabolin. So, the Testosterone Propionate dosage should be 500mg per week combined with 25mg per day for ten weeks and Deca. The dosage should be continuing for the first four weeks by taking 400mg per week for satisfactory results.
The 10-week Trenbolone / Test Pro Cycle
The intermediate steroid cycle can consist of testosterone propionate and trenbolone acetate. Users are expected t inject the compound in their body three times for ten weeks. The breakdown for the use of trenbolone / Test pro cycle should be as follows:
- From week one to ten-300mg per week Test Propionate inject 100mg or eod from Monday/Wednesday/ Friday.
- From week one to ten – 300mg per week Trebolone inject 100mg or eod within Monday/ Wednesday/ Friday.
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The cycle mentioned above will enable users to load the compounds in their syringes. In the entire cycle, you should use 0.5mg or eod Arimidex. Make sure you start Post cycle therapy when you are done taking the injection within three days. Also, go for 100mg daily Clomid within the first ten days and go on with the 50mg daily Clomid for the next ten days.
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Find Out About the Post Cycle Therapy for Testosterone Propionate
After long term use of the Testosterone propionate. There is a need to give the body a chance to recuperate and rejuvenate to the natural state. That is where the post-cycle testosterone propionate therapy comes in. It is the process users go after completing steroid cycles. This process aims to enable the body to start producing the hormone naturally without the use of the steroid. Completing a steroid cycle without backing it up with post-therapy is dangerous. It can lead to dependency on the steroids for the body to function the right way.
Many people do not know the need for the Post cycle therapy known as PCT. That is why some people are a victim of side effects that comes as a result of long term use of the steroid. More so, embark on long term use of steroids to avoid facing the dark side of the product. If you avoid going through PCT, your body will find it challenging to get back to normal, which may result in permanent replacement therapy.
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The time to start the PCT is not definite, as some users will begin immediately they complete the second or third days of their cycle. The length of the cycle determines the start day for the PCT. More so, if you embark on the longer Testosterone Propionate cycle, you may need to longer PCT to bring your body back to the normal. When it comes to the Testosterone Propionate solo cycle, users are expected to start their PCT within the first five days of their cycle completion to ensure its effectiveness. But, when you want to take PCT, there are some results to expect.
The Result to Expect From the Use of Post Cycle Therapy
There are certain things you need to know when you want to start your PCT after the completion of your steroid cycle. One of the things you should expect when you start your post cycle therapy is that you will not be able to work out as hard as you used to do when you are taking the steroids. Strength reduction is one thing to expect when you complete your steroid cycle and begin the PCT.
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Although you may not lose your gains when you start to take the PCT. You may feel tired or not pump as you use to do for your workout when you are in the steroid cycle. Therefore, you should have the right mindset when you begin your PCT to enable you to continue to get the right result you expect. Taking it easy on yourself is necessary when you want to go through the process to assist your body to recuperate. Regain its natural form and start production of the hormone.
Where You Can Buy Testosterone Propionate for Complete Cycle
Getting testosterone propionate is not difficult, as there are many dealers available on the internet. Also, it is among the cheapest or most affordable steroids available in the market today. If you are in the United States, you may find it challenging to get Testosterone Propionate. It is among the illegal steroids when taking without a prescription. Therefore, you should be careful when placing an order for this product with a prescription, as that can cause trouble. But, if you are buying after prescription, get it from the internet without wasting issues.
Steroids, such as Testosterone Propionate are popular among bodybuilders and sports enthusiasts. The bodybuilding and fitness industry is the place where Test Pro is used due to the effect of boosting muscle mass and enhancing performance. To reduce the side effects associated with the Test Pro, you should follow up with the recommended dosage and cycle duration base on your experience. It is what you need to boost your workout performance and grow your muscle mass and strength. To make sure other steroids work in the body without dangerous side effects, get a base steroid.
The best option for the base steroid is the Test Pro. So, you will be sure of getting the result you need when you take advantage of the Testosterone Propionate cycles as recommended. The PS solo cycle is good, as it helps the body returns to its natural form of hormone production. Take time to check through the Testosterone dosage base on your experience before making purchase online. Also, you should have in mind of the post cycle therapy to ensure your body returns to the normal way of producing hormones naturally.
10 Steroid Cycles for Different Goals (Newbie, Bulking, Cutting, Strength)
Steroid Cycles usage comes along with its own rules and only those who stay true to such rules usually survive long enough to experience the benefits. One has to keep in mind the correct dosage, length of the cycle and have an idea how best they can minimize the side effects. Whether you are a beginner or a seasoned steroid user, such rules are important and should be at your fingertips to help you get maximum benefits.
Here, we will focus more on the cycling part. People use steroids with different goals in mind. Mostly, steroids are meant to help in bulking, improving strength as well as performance and also to cut down the fat content of the body. To achieve these goals, you have to adapt a certain pattern of steroid usage, which is referred to as a cycle. You will get to know which steroids cycles are best for based on what you need to achieve using steroids in this article.
How Important Is Cycling?
Before going into cycling the steroids, it is important that you get to understand what actually cycling is and how it can help you achieve your goals. Cycling involves use of steroid for some period, pausing for some period and then continuing. Most steroid users will take them for usually about 6 to 16 weeks then either low dosage or even no steroids at all in the following few weeks. There are several reasons as to why the users, more specifically athletes cycle the steroids. Some of these reasons include:
- Athletes will target to have high performance during competitions so it is a way of ensuring that the benefits come at the right time and not go to waste.
- It is a way of ensuring that they are not easily detected by sports officials considering that most of these steroids are illegal and being detected will lead to automatic disqualification.
- Cycling is also a way of ensuring that adverse effects of the steroids are highly minimized and do not affect the health of the athlete.
- Cycling also comes in importantly as a way of reducing tolerance development, which may otherwise be disastrous to the career of the athlete.
Other related patterns of steroid usage
Apart from cycling which is a major part of our discussion here in this article, there are other patterns of steroid usage that you may want to know. These include pyramiding and stacking.
Just like a pyramid, pyramiding in steroid usage involves steady increase in the dosage or sometimes in the frequency of steroid used until a stage usually referred to as mid-cycle. At mid-cycle, the dosage or frequency is usually high and this will automatically be followed by gradual reduction to zero. The time of pyramiding has been estimated to be around 6 to 12 weeks after which the user is expected to engage himself or herself in exercise in the absence of the steroids.
People who follow this pattern of steroid usage claim that it has an effect of making the body adjust to high dosage at the right time. The drug free period that follows is believed to help the body synchronize with the normal hormonal functioning of the body. Obviously, this is something which has not been proofed scientifically and therefore no one is sure whether it is true or not.
Another important pattern that you can encounter among some steroid users is the stacking pattern. Stacking refers to combining the different types of steroids and taking them at the same time. This includes using both injectable steroids as well as oral steroids. Those who follow this pattern believe that when you combine different steroids, they combine and interact in a manner that will lead to a greater and more pronounced effect.
Just like pyramiding, no single scientific evidence exist to support this idea although it has proofed to work with some individuals. As such therefore, it has never been applied for medical purposes in cases where steroids are being used to cure some form of disease conditions. Stacking may be between:
- Injectable steroids and oral steroids.
- Steroids that act over a short period of time and those that act over a long period of time.
Steroid cycles for different groups
Steroid use has become a common practice nowadays. This is especially when it comes to weight lifters usually in the age bracket of 20 to 30 years. Both sexes also use the steroid although less common among females. We will explore steroid cycle among groups such as beginners, those with the intention of bulking, those who want to cut and even those who look for strength in steroids.
Newbie Steroid Cycles
With steroid usage becoming more and more common. It is not surprising that someone may wonder how he or she may begin using him or her and which steroid to start with. Focusing on the right steroids should always be a priority for beginners. It is not wise to just begin and take a very toxic steroid in the sense of getting the best result at ago. This will lead of course to severe side effects, which may not be what was the intention of the user. For newbies therefore, the best cycles include the one discussed below.
1 Anavar Only Cycle
For the first Anavar only cycle, one has to take 15 mg per day for the first 3 weeks followed by 20 mg per day for the remaining 3 weeks. This is especially designed for male beginners in steroid usage. For the second cycle, one needs 20 mg per day for the whole period and can usually be increased to about 8 weeks.
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Anavar is a steroid, which has been approved by FDA to be used strictly for medicinal purposes. However, if you are a beginner who wants to gain lean muscles and loose sufficient amounts of fat without severe side effects, then Anavar is good choice for you to try out.
G.D Searle and co. first launched Anavar in 1962 with the name Oxandrolone that of course later changed to Anavar. It quickly found its way among bodybuilders until it was burned in 1989 for those who use it for non-medicinal purposes.
Pros of Anavar
- Significant increase in mass of muscles
Anavar causes a significant and gradual increase in muscle mass, which makes it a favorite among beginners. It is not as strong as other agents so there are smaller side effects. It just requires a smaller to moderate dose of Anavar to bring about an increase in muscle mass of course when using the correct amount of calories every day.
- Reduction in body fat
Anavar is a good steroid when it comes to cutting for beginners as well as other steroid users who want to cut down on the fat content of the body. This will be effective if one accompanies its usage with a diet that is deficient in calories.
- Reduced water retention
Apart from reducing body fat, Anavar is also great for reducing water retention in the body. It helps eliminate excess water and distribute the fluids more effectively. As such, it will lead to hypertrophy and appearance of pumps since most water is confined to the cell. One visible sign of reduced water retention is increase in vascularity.
- Produces muscles pumps and full muscles
Because of reduced water retention, Anavar will make your muscle have pumps that are more prominent.
- For strength
Steroid newbies who have a goal of gaining strength will find this a very useful steroid and therefore a very good one to get started in their cycle. It is not however a very effective steroid for strength but its few side effects make it effective for beginners.
Cons of Anavar
Besides being a nice steroid for beginners, it happens that any steroid that is used has its bad side as well. Here are some of the cons of using Anavar.
- Increased blood pressure.
- Hepatic toxicity.
- A reduction in testosterone level.
- Depression and anxiety.
- Hair loss.
2 Testosterone only Cycle
Another cycle that will be of importance to newbies in steroid usage is the Testosterone only cycle. The cycle runs for 7 good weeks and encompasses 200 mg per day of testosterone for the first 2 weeks, 300 mg per day for the next 3 weeks and finishing with 350 mg per day for the remaining 2 weeks.
In the first cycle, the appropriate testosterone steroids are testosterone Cypionate and testosterone enanthate. These two are ester and have a common characteristic of acting slowly which is why they are the best for beginners.
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Pros of Testosterone
- Testosterone helps improve muscle development when used at the right time and in the correct dosage amounts.
- For medical purposes, testosterone can help in treatment of erectile dysfunction in men who have such problems.
Cons of testosterone
- Increased hair loss leading to baldness.
- Increased chances of developing heart related conditions such as hypertension and heart attacks.
- Reduced quality of sleep otherwise called sleep apnea.
- Gynecomastia in males.
Most of these problems do not develop immediately however. They only develop on frequently using the steroid for prolonged periods. Thus, for disciplined athletes, they rarely encounter such problems.
3 Dianabol only Cycle
Another steroid cycle for beginners is the Dianabol only cycle. The cycle runs for a period of 6 weeks and involves 20 mg per day for the first 2 weeks followed by 25 mg per day for the remaining 4 weeks. The dosage is a bit stronger and it is recommended for those beginners who are willing to endure slightly more side effects compared to the other 2 cycles.
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Dianabol is a very strong steroid, at least stronger than both testosterone and Anavar for beginners. As such, one can expect to gain more muscles as compared to when using the other 2 steroids. It commonly liked by beginners who are afraid of injection but want to have stronger muscles since it is an oral steroid. The active agent in Dianabol is methandrostenolone, which is one that causes increase in muscles over a very period of time.
Pros of Dianabol
- D-bol is able to help one pack on muscles within the shortest time possible compared to other steroids.
- It has strength building capabilities again over a short period of time. On average, one can expect to about forty pounds within a short period of time.
- The steroid is strong when it comes to losing body fat. Although it is a bulking agent, it helps in getting rid of excess fat too and in the process enhancing the tone of muscles.
- When used, d-bol has this effect help one gain stamina and intensity during workouts.
Cons of Dianabol
- Development of acne and hair loss leading to baldness.
- Development of cardiovascular conditions due to increase in levels of bad cholesterol.
- Hepatic toxicity is a common and serious problem caused by Dianabol since it is a c-17 alpha alkylated steroid.
- It can also lead to aggressive behavior and mood swings.
- Development of breasts in males.
Being illegal, D-bol has legal alternatives, which thankfully have no such tough side effects.
Bulking Steroid Cycles
Bulking is all about gaining muscles abundantly. It involves either packing on muscles or focusing on having lean muscles with the intention of retaining no water and getting ripped. Therefore, the cycles that should help one bulk should take into consideration either of the two aspects. Some of the most common cycles that can of great importance if you need to bulk are highlighted below.
4 Anadrol only Cycle
Anadrol only cycle stretches over a period of 6 weeks. You take 50 mg per day of the active ingredient in Anadrol for the first 3 weeks and then increase the dosage to 75 mg per day for the remaining 3 weeks. The cycle fits those individual who are in need of massive muscles and who in the past have not interacted with this steroid. For those who have interacted with this steroid, they can easily stretch some limits for example adding the cycling time to 8 weeks and even the dosage to 100 mg per day.
Anadrol is a very strong steroid to the body especially when it comes to bulking. Being such strong, it is not highly recommended for beginners unless they have gotten used to testosterone already or even Dianabol. Even so, they will need low to moderate amounts to be able to tolerate the steroid.
Pros of Anadrol
- It is a good steroid when one wants to gain massive sizes of muscles.
- It is also good for gaining sufficient amount of strength.
Cons of Anadrol
- Increase in blood pressure beyond dangerous levels.
- It is toxic to the liver being an oral steroid.
5 Anadrol and Deca Cycle
We have already talked about stacking before and here is how it can relate to cycling. You basically stack Anadrol and Deca Durabolin, another less strong steroid. The cycle runs over a time period of 8 weeks and you typically start off with 400 mg Deca Durabolin for the first 2 weeks followed by a similar dosage for the remaining weeks but of course with 50 mg per day of Anadrol for the first four weeks and increasing the dosage to 75 mg per day just like the Anadrol only cycle.
Why use the Stack?
Stacking deca and Anadrol will come a long with more effects than using Anadrol alone. Deca, being a milder steroid will help minimize the side effects associated with Anadrol.
Pros of using the stack
- The combination is more potent compared to using Anadrol alone.
- Improves sexual health unlike when Deca is used on its own.
Cons of the stack
- Suppression of natural testosterone production.
- Likelihood of increased water retention.
6 Anadrol and Test Cycle
Another wonderful cycle that can help in bulking include stacking Anadrol and Testosterone. This is a slightly more powerful alternative to the cycle above, which uses Deca Durabolin instead of Testosterone. It runs over a shorter period of time of 6 weeks. The dosage for Anadrol is the same as for the Anadrol only cycle while testosterone involves 200 mg per day for the first 2 weeks, 300 mg per day for the following 3 weeks and finishing off with 350 mg per day for the last one week.
Why the stack?
Being more powerful than the previous stack, the cycle will only be of importance to those well-advanced bodybuilders. These should have also been ardent users of Anadrol and successfully.
Pros of the stack
- Massive muscles are gained and are exceptional.
- Strength is also gained more that the above stack.
Cons of the stack
- Increase in blood pressure which may not be good for your health.
- Increased water retention.
- Reduced production of natural testosterone.
- Hepatic toxicity.
- Probability of developing gynecomastia in females.
7 Test and Deca Cycle
Testosterone and Deca Durabolin can be combined to produce one of the best-stacked cycle for bulking. It is great because it is considered one of the safest cycle that one can use to get bulk. It involves 200 mg/day of each of the two steroids for the first 3 weeks, 300 mg/day for the following 4 weeks and finishing with 200 mg/day.
Pros of the stack
- It is good for giving strength and size to the muscles.
- Low risk of gynecomastia.
Cons of the stack
- Hepatic toxicity is likely to occur.
Cutting Steroid Cycles
Cutting is an important phase in the lifespan of the bodybuilder, where they try to loose fat but at the same time trying to maintain the mass of the muscles. Steroids involved should therefore be ones that can burn sufficient amounts of fats while preserving the muscle mass that has been build. Here are some great cycles that can be used to cut.
8 Winstrol only Cycle
The winstrol only cycles stretches over a period of 6 weeks with 20 mg/day for the first 2 weeks then increasing to 25 mg/day for the remaining time period.
Winstrol has been known as the best Cutting steroid. It is cheaper than Anavar, which is also a good cutting steroid hence people tend to go for it. Its ability to help maintain the muscle gained is superior to that of Anavar but the only problem is that it has stronger side effects.
Pros of Winstrol
- Leads to massive muscles gains.
- Good at making someone shredded.
Cons of Winstrol
- Increase in blood pressure which may not be good for one’s health.
- Hepatic toxicity.
- Acne and facial hair loss.
9 Winstrol and Trenbolone Cycle
Winstrol can also be stacked with trenbolone and be used in a cycle to produce the best cutting effects on the body. The dosage for winstrol of course remains as the one above but tren should be taken in doses of 150 mg/day for the first 4 weeks and then increasing to 225 mg/day for the remaining period.
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Why the stack?
With Tren in the picture, it means there will be more of the shredding.
Pros of using the stack
- More fat burning and drying out effect compared to when using Winstrol alone.
- Enhanced muscle gains.
Cons of using the stack
- Suppressed testosterone production.
- Increased blood pressure to dangerous levels.
10 Proviron and Winstrol Cycle
Apart from Proviron, Winstrol can also be stacked with Proviron to bring about cutting. The dosage for Winstrol is maintained while for proviron, 25 mg/day are used for the first week followed by 50 mg/day for the remaining period.
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Why the stack?
This stack produces a very well ripped body more even than Winstrol and tren.
Pros of the stack
- Great stack for removing water from the muscles.
Cons of the stack
- Increase in high density lipoproteins hence cardiac related problems.
Different cycles are used to achieve different purposes as seen in this article. Most of the cycles however serve more than just the intended purpose and it is good that way. You should be able to find the right cycle, which favors you according to which group you fall into.
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