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Liver Damage While On Oral Steroids

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            Steroids consumption is associated with a range of side effects, but when it comes to oral steroids liver damage is the most common. For this main reason, most of the steroid users advice to use injectables instead of orals which bedevil the good activity of liver.

          In spite of this, oral steroids continue to be largely used by people worldwide. How can this be explained? First of all, injectable steroids can be detected in the blood long time after ending a steroid cycle. In case of orals, traces can be found few weeks after the last ingested pill.  It may seem a long time too, but in comparison with injectables, this frame of time is quite shorter.

            On the other hand, there are individuals who fear needles and will do all to avoid dealing with them. In this case, the oral injectable is going to be used to replace the gains injectable can cause in the human body. Oral steroids are more convenient to use but are while less effective than injectable.

How Is Liver Damaged While Running Oral Steroid Cycle?

Liver Damaged While Running Oral Steroid Cycle

             Liver is one of the most important organs in human as that if it shuts down we have only 2-3 days to live.  It’s the “cleanser” of the body, helping to get rid of toxins. Fortunately for us, the liver has the capacity to regenerate and be functional even when 75% of it is damaged.

                  All 17A oral steroids are modified in a way to avoid degradation in the liver and be able to get in the blood. These kinds of steroids are toxic to the liver because they inhibit the excretory function of the liver. Likewise, the liver can get rid of toxic and they accumulate in the body.

               Known as cholestasis this is the most common disease caused by 7aa oral steroids are blamed for. If no action is taken then after a while this disease worsens and may turn into cirrhosis, a stage where the action begins to slow down. Worth to be mentioned cholestasis is not a lethal disease and is reversible if needed measures are taken on time. The best is to avoid getting to this stage at all, as the ideal is to keep your liver safe instead of trying to treat. The things get worse when two 17A oral steroids are taken concomitantly. Never admit this mistake. Always try to cycle an oral steroid along with an injectable one, this being the smart way of using steroids.

To know more "Can Steroids Cause Liver Damage" can check out this video below

What are The Most Liver Toxic Oral Steroids?

Most Liver Toxic Oral Steroids

           Don’t put all oral steroids in the same light as not all of them are liver toxic. Some of them are more toxic than others, while a minority has no bad influence on the liver at all.

Top Most Liver Toxic Oral Steroids are:

  • Superdrol
  • Dymethazine
  • Halodrol
  • Epistane
  • DHEA
  • Epiandrosterone

         The more potent is the steroid, the higher is the toxicity level it carries on. Therefore, avoid using a powerful oral steroid when looking for fast and impressive muscle gains.

Top of Less Liver Toxic Oral Steroids:

           So, only 17-aa steroids are liver damage steroids, while all other steroids have minor to no influence at all. A good idea is to stack a 17aa steroid with a known one in order to keep your liver function while enjoying noticeable gains in muscle mass. Now you have know that Oral steroids and liver damage are only caused by the use of 17-aa steroids.

Symptoms of a Damaged Liver:

Symptoms of a Damaged Liver

              When your liver function is perturbed because of oral steroid use there are series of signs that you have to worry about. Pay a close attention to your overall feeling when running a steroid cycle to be able to prevent any disease before it will too late.

Here are Some of the Signs that Should Alarm you When Taking Orals:

  • Lowered appetite;
  • Fever associated with nausea (many take it as a cold, but it is not);
  • Itchiness;
  • Yellowish skin or eyes;

          Whenever one of these signs occurs is time to take a break and revise what you are doing wrong. The earlier you acknowledge what happens in your body and give a hand of help, the higher chances to pass through a cycle with your liver function untouched. The best would be not to wait for these signs, but simply take enzymes before and after a steroid cycle. A few weeks later after the cycle is finished repeat the tests and see how it shows. This way you will have a closer look at your liver situation.

Must read:: Top 20 Liver Detox Products and Anti-Estrogens on Amazon

Products That Help Keep Liver Health While on Steroids:

Products That Help Keep Liver Health While on Steroids

               As we said is better to prevent than to treat. A range of supplements available online is able to ensure a proper function of the liver while taking 17aa steroids. LIV 52 and Milk Thistle, Essentials are just a few of them, while a simple search on Google would list you a  longer list. Whatever you choose, make sure you have one of these supplements in your cycle.

              If you already have liver problems than taking 17aa steroid is a bad idea. Thier use will worsen your condition so that it can turn into something irreversible. Go with injectable in this case or use non-17 aa anabolics.

             Protect your liver before it is too late. Make sure your liver is 100% health before getting involves in a 17aa steroid cycle and make sure you add in some supplements able to help your liver cope with bad effects of steroids. Do you test and keep an eye on signs which talks about a liver problem.

Must Read Our Article: Anabolic Steroids, Liver Function and AST and ALT Blood Test

Building muscle mass is what I like to talk about. If your aim is to build a solid body, then my posts would be very beneficial to you. I always want to know your opinion, so don't hesitate to drop a line below or contact me.

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Counteracting Anabolic Resistance with Adaptogens in Aging Men

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As people age, maintaining muscle mass and strength becomes increasingly challenging due to a natural condition called anabolic resistance. This phenomenon, where muscles become less responsive to exercise and protein intake, can start as early as age 40. However, adaptogens—herbs that help the body adapt to stress—are emerging as promising allies in combating this resistance and promoting muscle health.

Understanding Anabolic Resistance Symptoms

Aging athletes may experience several symptoms of anabolic resistance, including:

Decreased Muscle Protein Synthesis

Muscles become less responsive to protein, affecting growth and recovery.

Increased Cortisol Levels

Chronic stress raises cortisol levels, which can lead to muscle breakdown.

Hormonal Decline

Natural decreases in testosterone and growth hormone reduce muscle-building capacity.

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Top Adaptogens for Muscle Health

Some of the most commonly used adaptogens include Ashwagandha, Rhodiola Rosea, and Panax Ginseng. Their key benefits are:

Ashwagandha

    • Supports testosterone levels.
    • Reduces cortisol, improving recovery and muscle maintenance.
    • Enhances endurance for sustained workouts.

Rhodiola Rosea

    • Lowers fatigue and increases stamina.
    • Reduces stress, supporting muscle retention.

Panax Ginseng

    • Boosts energy levels for longer, more effective workouts.
    • Supports immune function, aiding in recovery.

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How Adaptogens Support Muscle Tissue and Overall Health

Adaptogens help counteract anabolic resistance by:

Regulating Hormones

Ashwagandha may optimize testosterone and growth hormone levels, essential for muscle maintenance.

Lowering Cortisol Levels

High cortisol can exacerbate anabolic resistance. Adaptogens like Rhodiola and Ashwagandha help reduce cortisol, fostering a more anabolic environment.

Enhancing Energy and Endurance

Rhodiola and Ginseng boost energy levels, helping athletes maintain workout intensity, crucial for combating anabolic resistance.

Boosting Recovery and Reducing Fatigue

Ashwagandha aids muscle recovery, and Rhodiola reduces fatigue, both vital for consistent training intensity.

Tips for Integrating Adaptogens into Your Routine

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To incorporate adaptogens into your daily life, consider these tips:

Start Small

Begin with a lower dose to gauge your body's response.

Cycle Use

Use adaptogens for 6-8 weeks, then take a short break to reset and maintain their effectiveness.

Choose Quality Supplements

Opt for third-party tested and certified supplements to ensure potency and purity.

More Options to Counteract Anabolic Resistance in Older Men

Related Article: Peptides Vs Steroids - A Complete Guide 

When it comes to counteracting anabolic resistance in older men, it's important to consider both safety and efficacy. Here are some options that might be beneficial:

Selective Androgen Receptor Modulators (SARMs): These compounds are designed to mimic the effects of anabolic steroids without the severe side effects. They can help increase muscle mass and strength.

Testosterone Boosters: Supplements like Adaptophen contain natural ingredients such as Tongkat Ali, Siberian Rhodiola Rosea, and Elk Antler Velvet, which are promoted to boost testosterone levels, improve muscle growth, and aid recovery.

Human Growth Hormone (HGH): HGH supplements can help increase muscle mass and strength, but they should be used under medical supervision due to potential side effects.

Ecdysterone: This compound is found in certain plants and has been shown to have anabolic effects similar to anabolic steroids but with fewer side effects.

Turkesterone: Another natural compound that has shown promise in increasing muscle mass and strength without the harsh side effects of anabolic steroids.

It's crucial to consult with a healthcare professional before starting any new supplement regimen, especially if you have underlying health conditions or are taking other medications. They can help you determine the best course of action based on your individual needs and health status.

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Recommended Exercises to Restore Muscle In Older Men

Restoring muscle loss in older men can be effectively achieved through a combination of resistance training and functional exercises. Here are some of the most effective exercises:

Dumbbell Squats: These help build lower body strength and muscle mass. Stand with feet shoulder-width apart, holding dumbbells at your sides, and squat down while keeping your chest up.

Incline Dumbbell Bench Press: This exercise targets the upper chest and shoulders. Lie on an incline bench, holding dumbbells, and press them upwards until your arms are fully extended.

Chest-Supported Dumbbell Rows: Great for strengthening the back muscles. Adjust the bench to an incline, chest-supported, and pull the dumbbells towards your torso while keeping your back straight.

Planks: Excellent for core strength and stability. Hold a forearm plank position, keeping your body in a straight line from head to heels.

Bird Dogs: This exercise improves core strength and balance. Start in a tabletop position, extend one arm and the opposite leg, and hold for a few seconds before switching sides.

Bodyweight Exercises: Exercises like push-ups, lunges, and step-ups are also beneficial for maintaining muscle mass and overall strength.

Incorporating these exercises into a regular workout routine can help combat muscle loss and improve overall fitness. Remember to start slowly and gradually increase the intensity to avoid injury.

Conclusion

While adaptogens are not a substitute for a balanced diet or structured training, they offer a natural way for aging athletes to manage anabolic resistance. By supporting hormonal balance, reducing stress, enhancing energy, and aiding in recovery and fatigue, adaptogens like Ashwagandha, Rhodiola Rosea, and Panax Ginseng can help athletes, especially those over 40, stay strong and healthy as they age.

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Steroids

Tips on How to Store Peptides and HGH

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When peptides are mixed with bacteriostatic water (BAC water), their longevity is highly influenced by how they are stored. Correct storage is crucial, as improper conditions can compromise their quality and reduce their efficacy.

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Key Storage Guidelines

Room Temperature: Peptides tend to degrade rapidly at room temperature, lasting only a few hours to a day. It's best to use them immediately in this condition.

Refrigeration (2-8°C): When stored in a refrigerator, peptides mixed with BAC water can remain stable for 2-4 weeks. However, some peptides may degrade more quickly than others, so limiting storage to around two weeks is safest.

Freezing (-20°C or lower): For prolonged storage, freezing is the best option, maintaining peptide stability for several months. It is important to avoid multiple cycles of thawing and refreezing, as this can degrade the peptides.

It's important to note that storage guidelines can differ depending on the specific peptide, so always check for the particular recommendations to ensure maximum longevity and effectiveness.

NOTE: Peptides reconstituted with Sterile Water only remain potent for 2-3 days, even under ideal storage conditions. This is because sterile water lacks the antibacterial properties of BAC water, leading to faster bacterial growth and peptide degradation.

Finding Containers to Store Peptides and HGH

You can find containers for storing peptides and HGH at various online retailers and specialty stores. Here are a few options:

Edge Peptides: They offer a range of storage containers suitable for peptides, including glass and high-quality plastic vials.

Peptide Sciences: This site provides information on peptide storage and offers appropriate containers.

Muscle and Brawn: They have guidelines on peptide storage and sell containers designed for this purpose.

Make sure to choose containers that are chemically inert, such as glass or high-quality plastic, to avoid any reactions with the peptides. Additionally, ensure the containers are tightly sealed to prevent contamination and degradation.

What Would Be the Best Peptides and HGH for Beginners?

For beginner bodybuilders and athletes, it's important to start with safe and effective options. Here are some of the best peptides and human growth hormone (HGH) supplements:

Peptides for Muscle Growth

Ipamorelin: Stimulates growth hormone production, aiding muscle growth and fat loss.

CJC-1295: Enhances growth hormone release, promoting muscle growth and improving sleep quality.

Hexarelin: Stimulates growth hormone release, aiding muscle gain and cardiovascular health.

Sermorelin: Increases growth hormone production, beneficial for muscle growth.

GHRP-6: Stimulates growth hormone release, increasing energy levels and aiding muscle growth.

HGH Supplements

CrazyBulk HGH-X2: Boosts HGH production, increases energy levels, and helps build muscle mass.

HyperGH 14x: Promotes muscle growth and improves performance.

GenF20 Plus: Maintains optimal HGH levels, aiding in muscle growth and anti-aging.

PGH-1000: Enhances strength and stamina.

Sytropin: Supports physical fitness, anti-aging, and andropause.

Summary

Storing peptides and human growth hormone (HGH) properly is crucial for maintaining their effectiveness and ensuring safety. Peptides should ideally be stored in a refrigerator at 2-8°C for up to 2-4 weeks when mixed with bacteriostatic water, while freezing them at -20°C or lower extends their stability for several months, but avoid thawing and refreezing. When reconstituting peptides, use bacteriostatic water instead of sterile water to maintain potency for a longer duration (2-4 weeks versus 2-3 days). Use chemically inert containers, like glass or high-quality plastic vials, and ensure they are tightly sealed. Maintain sterility during reconstitution and storage to prevent bacterial contamination.

Use reconstituted peptides as soon as possible to avoid degradation in solution. Popular peptides for muscle growth include Ipamorelin, CJC-1295, Hexarelin, Sermorelin, and GHRP-6, while CrazyBulk HGH-X2 is a common supplement to boost HGH production. Always check the specific storage recommendations for each peptide, as they can vary.

Remember, it's crucial to consult with a healthcare professional before starting any new supplement regimen to ensure it's safe and appropriate for your individual needs.

Must Read: Targeted Training for Individual Muscle Groups 

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Ostarine For Beginners: The Ultimate Guide

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Ostarine, also referred to as MK-2866 or Enobosarm, is among the most extensively used and researched Selective Androgen Receptor Modulators (SARMs). Initially developed to combat muscle-wasting diseases, it has gained immense popularity among athletes and bodybuilders for its muscle-preserving and performance-enhancing benefits.

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How Does It Work?

Ostarine selectively binds to androgen receptors in muscle and bone tissues, promoting protein synthesis and osteogenesis. Unlike anabolic androgenic steroids (AAS), which interact with androgen receptors throughout the body, Ostarine specifically targets certain tissues, reducing the risk of unwanted side effects such as hair loss, high estrogen levels, prostate enlargement, or virilization in women.

Practical Benefits of Ostarine

Muscle Preservation

Ostarine is well-known for its ability to maintain lean muscle mass, especially during calorie deficits. Studies have shown that it prevents muscle wasting while sustaining strength and endurance, making it ideal for cutting cycles (Dalton et al., 2011).

Muscle Growth

Although its muscle-building capacity is milder compared to stronger SARMs or AAS, Ostarine effectively promotes gradual, high-quality muscle gains without excessive water retention.

Improved Recovery

Athletes have reported enhanced recovery times with Ostarine. By reducing muscle breakdown and increasing nitrogen retention, it allows users to train more frequently and intensively.

Bone Health

Ostarine positively impacts bone density. Research indicates its ability to increase bone mineralization, potentially making it a therapeutic agent for osteoporosis (Narayanan et al., 2008). For athletes, this translates to a reduced injury risk and stronger skeletal support during heavy training.

Related Article: Legality of Steroids in Latin America 

Potential Side Effects

Mild Testosterone Suppression

Ostarine can suppress natural testosterone production, particularly at higher doses. Post Cycle Therapy (PCT) is recommended after cycles to restore hormonal balance.

Dyslipidemia

Like most SARMs, Ostarine can affect lipid profiles, potentially lowering HDL (good cholesterol) and increasing LDL (bad cholesterol).

Elevated Liver Enzymes

Some users report mild elevations in liver enzymes during use, though these usually return to normal after discontinuation.

Long-Term Effects

Unknown As a relatively new compound, the long-term effects of Ostarine on health are not fully understood.

How to Use Ostarine Correctly

Dosage and Cycle Recommendations

Ostarine is typically dosed at 10–30 mg per day, depending on the user’s goals and experience level:

For Cutting: 10–20 mg per day to preserve muscle and aid fat loss.

For Bulking: 20–30 mg per day to promote lean muscle gains.

Cycles generally last 6–8 weeks. Longer cycles or higher doses may increase the risk of side effects, including testosterone suppression. With a half-life of approximately 24 hours, Ostarine allows for convenient once-daily dosing.

Post Cycle Therapy (PCT)

We highly recommend PCT following Ostarine cycles, especially for doses exceeding 20 mg per day, to restore natural testosterone levels.

Ostarine Alternatives

For beginner bodybuilders looking for alternatives to Ostarine, here are some popular options:

  1. RAD 140 (Testolone): Known for its excellent muscle-building and fat-burning properties, RAD 140 is a favorite among those looking to gain lean muscle mass.
  2. LGD-4033 (Ligandrol): This SARM is highly effective for increasing strength and muscle mass, making it a great choice for beginners.
  3. Cardarine (GW-501516): Although not technically a SARM, Cardarine is popular for its ability to enhance endurance and fat loss.
  4. YK-11: This SARM is known for its ability to promote muscle growth and strength, similar to anabolic steroids.
  5. S23: Effective for cutting cycles, S23 helps reduce body fat while preserving muscle mass.
  6. Andarine (S4): This SARM is used for both bulking and cutting, offering muscle preservation and fat loss.

These alternatives offer various benefits and can be chosen based on individual goals and preferences. It's always important to research and consult with a healthcare professional before starting any new supplement regimen.

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Overall

Ostarine (MK-2866) is a versatile and beginner-friendly SARM, offering significant benefits for muscle preservation, recovery, and lean growth. Its selective action and mild side-effect profile make it an attractive option for athletes and bodybuilders seeking an edge in performance and aesthetics. However, responsible use, including appropriate dosing, cycle length, and post-cycle therapy, is crucial to minimizing risks and maximizing results.

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