Steroids

All About Post Steroid Cycle Therapy

Published

12 years ago

January 10, 2013

F Kyle

After ceasing, the steroid cycle body get in a situation where its natural testosterone production was repressed by androgens, and it need help to restore it. With no help, body turns into a catabolic state which causes loss of muscle mass gained during the steroid cycle. Namely for this purpose has been designed post cycle therapy, which includes a range of preparations and sports supplements, able to minimize the side effects of steroid use and to restore the natural production of user hormones.

Post cycle therapy is considered even more important than the steroid cycle itself. Adding muscle mass can be an easier task than maintaining it after steroid ceasing. This is the challenge, and post cycle therapy is the best tool for this. Most of the bodybuilder loss a big percentage of muscle mass gained during a steroid cycle, and this happens mainly because they ignore the importance of post cycle therapy.

Despite it called post cycle, there is a medication that has to be taken during steroid cycle itself. Usually, it is introduced at the beginning of the cycle and continue to be taken 2, 3 weeks after steroid cycle end up.

These are The Main Goals of Post Cycle Therapy:

-Prevent aromatization, which means no or minimal water retention side effect;
-Prevent the occurrence of gynecomastia (bitch tits);
-When taking a steroid, testicles decreased significantly in volume. Post cycle medications prevent testicular atrophy and oligospermia;
-Restore the natural production of testosterone;
-Keeping the muscle mass gained during the steroid cycle;

The most important to be taken during post cycle therapy are antiestrogens. These are all preparations for preventing first of all gynecomastia. Among the most common drugs from this group are Clomid, Nolvadex, and HCG.

Clomid (Clomiphene Citrate):

clomid-usa

Clomid (Clomiphene citrate ) is the most effective among antiestrogen drugs. It is perfect to obviate gynecomastia and restore natural testosterone production. It has almost no side effects, is considered a safe drug. One of the most reported side effects is blurred vision, but it occurs only in case of exceeding recommended doses. It can be found on tabs or liquid version and can be found in all market.

Clomid Dosage:

The most common dose of Clomid is 300 mg for the first day. Beginning with the second and till the 7th day, the recommended dose is 100mg per day. Further, Clomid should be taken in a dose of 50 mg per day. There is no need to split up the Clomid dose throughout the day, you can take it one time. Clomid has to be taken during all steroid cycle and 2, 3 weeks after it ceases.

Nolvadex ( Tamoxifen Citrate):

tamoxifen-tablets-nolva

Nolvadex (tamoxifen citrate) is a nonsteroidal agent and can be a great alternative for clomid. If you worry about Clomid side effects, you can safely choose to use Nolvadex. It can be taken once a day, since having a relatively long life. Mostly the administration rules are closed to Clomid: have to be taken during the all steroid cycle and few weeks after it ceases.

Nolvadex Dosage:

It depended on steroid cycle type. For moderate steroid cycle, those for beginners steroid users, you can follow these doses:

-In the very first day take 100 mg of Nolvadex
-Next ten days take 60 mg daily
-Final ten days take 40 mg per day.

Dosage pictures are changed depending on the length of steroid cycle and the types of steroid used during it. If you choose to use the more powerful steroid or opt for a longer cycle than the dosage of Nolvadex should be slightly increased.

For greater results, there are bodybuilders who choose to stack Clomid with Nolvadex. This is a quite good idea since it will prevent all side effects with greater success. But, be careful to dosage. A most common dosage of Nolvadex and Clomid used simultaneously look like this:

I day- 200 mg of Clomid and 40 mg of Nolvadex;
Next 20 days- 50 mg of Clomid plus 20 mg of Nolvadex.

HCG (Human Chorionic Gonadotrophin):

Along with Clomid and Nolvadex, HCG (Human Chorionic Gonadotrophin) is another very popular medicine used in post cycle therapy for helping the body to restore natural testosterone production. It is especially used during longer or heavier steroid cycles to prevent testicular atrophy, or rectify problems of atrophy if they already occurred.

HCG Dosage:

The best will be to use HCG in small doses, more frequently during a steroid cycle and after its ending. This will give you better results and minimum side effects. The most commonly used dose is about 500 IU and 1000 IU per day. Begin to take HVG after 2-3 weeks of a steroid cycle, and completed it a week before Clomid and Nolvadex use. This has to be done in order to prevent inhibition of Nolvadex and Clomid therapy.

Do not go for higher doses, since you risk to increase estrogen level, and this may cause the occurrence gynecomastia side effect. Keep in mind that 500 IU and 1000 IU per day of HCG will prevent testicles atrophy or rectify this is a problem. And this is the mandola of HCG use.

Testosterone Boosters:

What to Get to Get Ready

Testosterone Boosters are also included in post cycle therapy. Their main goal is to help to restore hormonal balance. Most popular preparations from this category are Tribulus Terrestris, 6-OXO, ZMA, Forskolin and D-acid aspartic. The length of this testosterone booster cycle is no longer than 4 weeks, and have to be taken one to three times a day.

Hepatoprotectors are another category of medication taking during steroid cycles. These drugs have protects the liver from the toxicity of many anabolic steroids. Usually, they begin to be taken during the second week of the cycle and continue 2, 3 weeks after its ending. Some of this medication are; Phospholipids (Essenciale), Alpha-lipoic acid, Arginine, and Ornithine. The recommendation is to take them in combination for greater effects.

Omega 3 has also to be taken during post steroid cycle. Its role is to normalize cholesterol and protect the heart and blood vessels. It should be taken during the whole steroid cycle and the next 2 weeks.

Cortisol blockers supplements lower cortisol level. Drugs from this group are being used to protect the muscles from damage after ceasing steroid cycle. Meantime they greatly burning fat and help you get shredded. Most common cortisol blockers drugs are Clenbuterol, Higher Power CortiShed, Muscle-Link Cort-Bloc, Goliath Labs Thermoloid, Cortislim, Cortiburn, Cortidrene, and others.

This is how post therapy steroid cycle looks and what it has to contain. It is up to you to choose what you will include, and what you will ignore but antiestrogens are a must. They will keep you away from the most common side effects of steroid use and will help your body to restore natural testosterone production.

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F Kyle

The "GYMRAT" of this blog, Pro-blogger and Fitness Instructor since 2008

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Steroids

Steroid Shops Review

Published

1 hour ago

May 23, 2025

Sane

osgear.se Reviews

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Most customers had an overall great experience with this source, especially with safety protocols. Products arrive within the stipulated time frame. Osgear provides a seamless online shopping experience, offering a diverse range of high-quality AAS steroid products that cater to various customer needs.

Their platform is intuitive and easy to navigate, making the purchasing process smooth and efficient. Delivery is reliable, with well-packaged items arriving within the expected timeframe. Customer service is highly responsive and professional, ensuring that inquiries and concerns are addressed promptly and effectively. In terms of pricing, Osgear strikes a balance between affordability and value, making it a great choice for shoppers looking for competitive rates without compromising on quality.

Overall, Osgear stands out as a trusted online store that excels in steroid, supplement and other PEPs' selection, service, and pricing, making it a dependable destination for convenient and satisfying shopping for your bodybuilding gear.

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Steroids

ACE-031: A Powerful Myostatin Inhibitor

Published

1 week ago

May 15, 2025

Sane

ACE-031 is a synthetic peptide designed to block myostatin, a natural regulator of muscle growth. Developed by Acceleron Pharma, it was originally studied as a treatment for muscle-wasting conditions like muscular dystrophy. By inhibiting myostatin, ACE-031 enables unrestricted muscle growth, making it appealing to athletes and bodybuilders seeking increased muscle mass and strength.

Benefits for Bodybuilders

ACE-031 offers significant advantages for bodybuilders aiming to maximize muscle growth:

Enhanced Muscle Development – By blocking myostatin, ACE-031 eliminates the biological limit on muscle expansion, allowing for significant increases in lean muscle mass.

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Improved Endurance and Fat Reduction – Users may experience enhanced endurance and reduced fat accumulation, which contributes to overall body composition improvements.

Accelerated Recovery – The peptide aids in muscle repair, shortening recovery time after strenuous workouts and enabling more frequent training sessions.

These benefits make ACE-031 a valuable tool for bodybuilders seeking superior performance and rapid results.

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Potential Side Effects

While ACE-031 delivers powerful muscle-building effects, it is not without risks:

Swelling in Limbs – Some users report fluid retention and swelling, particularly in the arms and legs.

Weakened Tendons and Ligaments – Rapid muscle growth may surpass the body's ability to strengthen tendons and connective tissues, potentially leading to strain or injury.

Unknown Long-Term Effects – Since human studies on ACE-031 are limited, the full scope of potential risks remains uncertain.

Given these concerns, careful monitoring and responsible use are essential.

Recommended Dosage and Cycling

Due to its potency, ACE-031 should be dosed conservatively:

Beginner Dosage – 1 mg per week, injected subcutaneously or intramuscularly, to assess tolerance.

Experienced Users – Up to 3 mg per week, but only with caution and close observation for adverse effects.

Cycling Approach – A typical cycle lasts 4–6 weeks, followed by a break to prevent desensitization and allow the body to reset.

Using ACE-031 responsibly within structured cycles helps mitigate risks and optimize benefits.

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Potential Alternatives to ACE-031

Here are 10 alternatives to ACE-031 that also function as myostatin inhibitors or support muscle growth through similar mechanisms:

Follistatin-344 – A potent myostatin inhibitor that promotes muscle hypertrophy by blocking myostatin activity.

BPC-157 – Known for its regenerative properties, it enhances healing and tissue repair, indirectly supporting muscle growth.

CJC-1295 – A growth hormone-releasing peptide that boosts GH levels, aiding in muscle development.

Ipamorelin – Stimulates GH release with minimal side effects, making it a safer option for muscle enhancement.

MK-677 (Ibutamoren) – A powerful GH secretagogue that promotes muscle growth and fat loss.

Sermorelin – Encourages natural GH production, supporting recovery and lean muscle gains.

Tesamorelin – Primarily used for fat loss but also aids in muscle preservation.

PEG-MGF (Pegylated Mechano Growth Factor) – Enhances muscle repair and growth post-exercise.

GHRP-6 – Stimulates appetite and GH release, supporting muscle mass gains.

Activin A Blockers – Experimental compounds that target the myostatin pathway to enhance muscle growth.

Each of these alternatives has unique mechanisms and benefits, so selecting the right one depends on your specific goals.

ACE-031 is available in several forms for purchase, depending on the supplier. Here are the common options:

Peptide Vial – Typically comes in 1 mg vials for reconstitution.

Pre-Mixed Pen – A ready-to-use injectable form for convenience.

Nasal Spray – An alternative delivery method for those avoiding injections.

Peptide Stacks – Some suppliers offer ACE-031 combined with IGF-1 LR3 for enhanced muscle growth.

You can find these forms from suppliers like PharmaLabGlobal and Direct Peptides.

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Overall

ACE-031 presents promising muscle-building advantages, making it a sought-after peptide among bodybuilders. However, due to limited research and potential side effects, users should approach it with caution, adhere to recommended dosages, and seek professional guidance to ensure safe usage.

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Steroids

Decoding IGF-1 LR3: A Guide to its Benefits

Published

4 weeks ago

April 25, 2025

Sane

IGF-1 LR3 (Insulin-like Growth Factor-1 Long Arg3) is a synthetic variant of IGF-1, a hormone produced by the liver in response to growth hormone (GH). Unlike GH, which works indirectly, IGF-1 directly facilitates the growth and repair of muscle cells.

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This modified version of IGF-1 is engineered to avoid binding with IGF-binding proteins, extending its half-life to 20–30 hours. As a result, it remains active in the body significantly longer than natural IGF-1.

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Many performance athletes incorporate IGF-1 LR3 post-workout to enhance muscle growth, speed up recovery, and support fat loss. When injected into specific muscle groups, it often produces localized effects. Additionally, it helps with nutrient distribution and, in some cases, improves insulin sensitivity.

On the other hand, human growth hormone (HGH) operates more broadly and indirectly, stimulating the liver to produce IGF-1 and offering more systemic benefits such as improved skin health, joint support, and fat reduction, albeit at a slower pace.

Typical IGF-1 LR3 doses range from 20–50 mcg daily, administered subcutaneously or intramuscularly, often following a workout.

Key Features of IGF-1 LR3

Enhanced Bioavailability: It avoids binding with IGF-binding proteins, increasing its potency.

Muscle Growth & Repair: Directly stimulates muscle cell proliferation and differentiation.

Improved Nutrient Distribution: Helps shuttle nutrients into muscle cells, supporting recovery.

Potential Fat Loss Benefits: Some users report improved insulin sensitivity and fat metabolism.

Mechanism of Action

IGF-1 LR3 interacts with IGF-1 receptors on muscle cells, activating pathways like PI3K-AKT and MAPK, which are crucial for cell growth and regeneration. This makes it a powerful tool for bodybuilders and athletes looking to optimize recovery and muscle development.

What Are the Top 10 Alternatives to IGF-1 LR3?

Here are some of the top alternatives to IGF-1 LR3, each with unique benefits for muscle growth, recovery, and performance:

BPC-157 – Known for its regenerative properties, it enhances healing and tissue repair.

CJC-1295 – A growth hormone-releasing peptide that boosts GH levels for muscle development.

Ipamorelin – Stimulates GH release with minimal side effects, making it a safer option.

MK-677 (Ibutamoren) – A potent GH secretagogue that promotes muscle growth and fat loss.

Sermorelin – Encourages natural GH production, supporting recovery and lean muscle gains.

Tesamorelin – Primarily used for fat loss, but also aids in muscle preservation.

Follistatin-344 – Inhibits myostatin, allowing for increased muscle hypertrophy.

PEG-MGF (Pegylated Mechano Growth Factor) – Enhances muscle repair and growth post-exercise.

GHRP-6 – Stimulates appetite and GH release, supporting muscle mass gains.

GHRP-2 – Similar to GHRP-6 but with fewer hunger-related side effects.

Each of these peptides has distinct mechanisms and benefits.

Must Read: Are Nootropics a Better Option to AAS?

Potential Risks Associated With IGF-1 LR3

IGF-1 LR3 comes with several potential risks, especially for bodybuilders using it to enhance muscle growth. Here are some key concerns:

Hypoglycemia (Low Blood Sugar) – IGF-1 LR3 increases glucose uptake in muscle cells, which can lead to dangerously low blood sugar levels if not managed properly.

Organ Growth – Since IGF-1 affects all tissues, excessive use may lead to unwanted growth in organs, increasing health risks.

Cancer Risk – IGF-1 plays a role in cell proliferation, and elevated levels have been linked to an increased risk of certain cancers.

Water Retention & Edema – Some users experience bloating and fluid retention, which can affect performance and aesthetics.

Joint Pain & Stiffness – Excessive IGF-1 levels may contribute to joint discomfort due to increased tissue growth.

Cardiovascular Issues – There is some concern that IGF-1 LR3 could contribute to heart enlargement or other cardiovascular complications.

Desensitization – Long-term use may reduce the body's natural IGF-1 production, leading to dependency

Overall

IGF-1 LR3's ability to bypass IGF-binding proteins makes it more potent but also increases the likelihood of desensitization with prolonged use. For those considering it, careful dosing and monitoring are crucial to mitigate side effects.