Steroids

Why Use Antioxidants During a Steroid Cycle.

Published

3 years ago

March 9, 2021

Antioxidants During a Steroid Cycle

Steroids are synthetic hormones designed for clinical use in managing various chronic diseases. Anabolic-androgenic steroids, derivatives of the male hormone testosterone, are used by athletes in sports. The aim in such instances is to boost muscle mass and increase performance and endurance. Also, they shorten recovery time between exercises. Inappropriate use of steroids is associated with several adverse effects. Their correct use is recommended to limit such outcomes, and antioxidants can help you.

Due to the varied uses and different desired outcomes, patterns of use have been established; cycling, stacking, and pyramiding. The steroid cycle refers to a pattern of steroid use intending to build body or muscle mass. Here, anabolic androgenic steroids are used in six to twelve weeks, followed by an off phase of several months. Pyramiding generally involves gradually increasing the dose of the steroids to a maximum level, followed by dose reduction. Another pattern is stacking, where various steroid combinations include other supplements.

Steroids in Sports

Athletes' desired outcomes categorize steroids as either bulking steroids- used to increase muscle mass or performance steroids- aimed to increase strength and endurance. Or cutting steroids- used to reduce weight (cut fat). Delivery routes are based on user preference and desired outcome. It can be oral, implants, injections, and creams or gels. They bind to the androgen receptors in the body, resulting in molecular interactions with the cell DNA. The ultimate result is to increase protein synthesis and subsequent cell growth.

Cycles for anabolic steroid use depend on the physical state of the user. Beginners and experienced users have different cycles. This limits the chances of developing adverse outcomes; for instance, it lowers the risk of suppressing one's hormone production. Also, it enhances higher efficiency and safety. An example of a steroid cycle for beginners includes turinabol 30-50mg/day for 9 weeks, testosterone enanthate 500mg/week for 8 weeks, and Dianabol 30-50mg/day for 6 weeks. Experienced athletes' cycle contains a combination of steroids, for example, nandrolone decanoate +sustanon, trenbolone enanthate plus testosterone, and boldenone plus testosterone enanthate.

What are Antioxidants?

Antioxidants are substances or elements that inhibit or reduce cell damage due to free radicals, reactive oxygen species, and other unstable molecules resulting from chemical reactions or physiological changes in the body. During a steroid cycle, antioxidants play a role in scavenging free radicals and other unstable compounds produced by skeletal muscles during exercise.

The roles played by these antioxidants include;
Prevent oxidative stress.
Reduce exercise-induced muscle damage.
Increase muscle endurance.
Shorten the recovery time after exercise.
Counteract neutrophil inflammatory response.

The roles listed above are discussed in detail as follows. Later, I will discuss various classes and types of antioxidants available.

Antioxidants Counteract the Effect of Oxidative Stress.

Antioxidants cushion the oxidative stress sequelae. Physical exercise increases the production of reactive oxygen species, nitrogen species, and free radicals and their accumulation within the muscle mass. A sustained balance between oxidation and reduction is important in maintaining muscle physiology. These reactive oxygen species comprise superoxide anions, hydroxyl radicals, and peroxyl radicals.

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Oxidative stress results from an imbalance between free radical production and the eliminating of physiological antioxidants. This imbalance with increased radical levels accounts for oxidative damage. Stress-sensitive signal pathways are activated, which play a role in the pathogenesis of chronic conditions such as cardiovascular conditions, metabolic syndrome, and insulin resistance.

Physical exercise's physiological importance in maintaining normal body function and health is accompanied by oxidative stress induction. During physical exercise, there is an increased demand for oxygen in the muscle tissue. It is estimated that oxygen uptake by the muscles increases by 10-20 folds. This increased influx in active skeletal muscles increases the formation of reactive oxygen species and free radicals. Their effect is to oxidize macromolecules, DNA, amino acids, polyunsaturated fatty acids, and proteins.

Basis of Antioxidants

The oxidized molecules form the basis for the development of chronic diseases. Reactive oxygen species accumulation results in muscle dysfunction and damage, prolonging recovery time. Antioxidants must counter these effects by eliminating formed reactive oxygen species and free radicals.

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Increased muscular activity is accompanied by increased metabolic rate and increased oxygen consumption by muscle fibers. This results in a subsequent temperature increase and reduced cellular muscle mass pH. These changes enhance free radicals' formation and accumulation in the muscle cells. Antioxidants protect the body from oxidative damage by reactive oxygen species and free radicals. Antioxidants protect against muscle damage.

During the steroid cycle, muscular activity increases with increased exercise levels. During this activity, muscle fibers stretch as a result of repeated use. Repeated contractions and relaxation create tension in skeletal muscles, causing the fibers to lengthen. Physical exercise increases oxygen influx within the muscle tissue. These active muscle fibers increase in size approximately by 100-200 folds. Normally, muscle fibers are adaptive to the level of stress experienced.

However, increased activity increases the production and accumulation of free radicals and reactive oxygen species. Their formation rate exceeds that of clearance by available antioxidants, both exogenous and endogenous systems. Their formation plays a role in muscle damage during physical activity. Antioxidants remove the reactive oxygen species, thus halting further muscle damage. A study by Cian McGinley et al. 2009 evaluated vitamin C and E's role in preventing muscle damage due to ROS due to exercise among sportspersons.

New studies on Antioxidants

The study used various supplementation mechanisms with variations in dosing, timing, and duration. The study's outcome showed that antioxidants reduce oxidative stress with a minimal role in preventing muscle damage. A similar study by Vilma Simoes Pereira et al. in 2015 aimed to find the effects of supplementation with dietary antioxidants on recovery following exercise-related muscle damage.

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Dietary supplementation of phytochemicals has been shown to reduce the effects of eccentric muscle damage due to exercise. Another study explained the findings above, emphasizing that the correct dosage and requirement should be provided to avoid toxicity or causing further muscle damage. An individual estimated requirement must be provided for muscle tissue's effective functioning and a better outcome.

Role in Modulating Inflammatory Response.

During the steroid cycle, individuals are involved in strenuous physical exercise. This activity alters the skeletal muscle state by increasing the length and that of tendons. This is a result of the adaptive activity of the muscle tissue to exercise, as discussed above. In the process, there is a muscle injury, which will trigger an inflammatory response. Muscle damage also results from the thermal effects and ischemia/reperfusion. Neutrophil leads to the accumulation of reactive oxygen species, thus increasing the burden of oxidative stress in the muscle cells.

Neutrophils are increased in circulation during exercise. Their increase subsequently increases the level of neutrophils associated with reactive oxygen species and corresponding oxidative stress. Another source of neutrophils during exercise is suggested to be the effect of free radicals on leucocytes, where they damage the DNA. A study confirmed that antioxidants modulate the neutrophil inflammatory response to exercise-induced stress.

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In that study dated December 7th, 2020, three groups were studied for 21 days. One group was on the antioxidant-supplemented beverage, and the others acted as control groups. Blood samples were drawn at the end of the exercise, and plasma and neutrophils were separated. Plasma creatinine kinase and myoglobin levels have elevated a confirmation of muscle damage due to exercise.

After measuring plasma oxidative bio-markers, it was found that it increased in all the groups, not on antioxidant supplements. On measuring neutrophil antioxidant enzymes, there was a notable increase in the control groups, confirming that the activity was reduced in the supplemented group. The activity of myeloperoxidases was increased significantly among the control groups. On the other hand, enzyme levels were elevated among those on antioxidant supplements. This confirmed the role of antioxidants in modulating inflammatory responses induced by exercise.

Increase muscle endurance and recovery and reduce recovery time.

Selected antioxidants have been shown to increase muscle endurance by reducing the delayed onset of muscle soreness. Polyphenols and other commercial antioxidants have been shown to have a moderate to good effect in lowering the delayed onset of muscle soreness. Other antioxidants have been shown to affect post-exercise muscle recovery positively. The ROS-scavenging effect of antioxidants reduces the number of free radicals and reactive oxygen species in skeletal muscles during exercise. These changes reduce muscle damage and thus increase muscle endurance during exercise. The formation of free radicals within the skeletal muscle has beneficial effects—the produced reactive oxygen species act as signaling pathways to enhance muscle protection from further physical stress.

Antioxidants

As defined above, they are free radical scavenging molecules. The overall effect of this function in to protect the cells from oxidative stress-induced damage. Their interaction with free radicals results in a chemical reaction that stabilizes these free radicals. In other words, the molecules can prevent oxidation or limit oxidation of other molecules. Oxidation refers to a chemical reaction that involves the transfer of electrons from one compound or element to the other (oxidizing agent).

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These reactions act as a source of free radicals, which start a chain of other harmful reactions to the cells. Antioxidants are mostly reducing agents in nature, thus preventing oxidation reactions by them getting oxidized in the process. A lack of antioxidants in the body or their limited availability will result in an oxidative stress state. This state is associated with a series of reactions that damage the cells and compromise function. Free radicals are associated with the pathogenesis of chronic diseases, for instance, cardiovascular diseases and cancers. Supplementation of antioxidants is beneficial because it provides the body's optimal physiological function and improves health.

Antioxidants can be endogenous or exogenous. Physiological antioxidants are naturally present in the body and comprise superoxide dismutase, catalase, and glutathione peroxidase. Exogenous antioxidants must be provided through an antioxidant-rich diet, synthetic antioxidants, and other supplements. Examples include thiols, vitamins C, E, and A, and polyphenols. Antioxidants can also be grouped as: 1. Natural antioxidants (primary), and 2. Synthetic antioxidants (secondary).

Primary antioxidants (free radical scavengers)

These antioxidants stabilize free radicals. They achieve this by breaking the chains of lipid radicals and converting them to a non-radical state or stable form. This group comprises antioxidants derived from phenols and secondary aromatic amines. Their structure makes them available in different molecular weights. They are further grouped as either mineral antioxidants, vitamin antioxidants, or phytochemicals. The mineral antioxidant serves as co-factors to enzymes involved in the anti-oxidation process. They comprise selenium, iron, zinc, magnesium, and copper.

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Their availability plays a bigger role in macromolecules' metabolisms, such as proteins and carbohydrates. Vitamins and antioxidants are vitamins that act as reducing agents. This comprises vitamins B, C, and E. Antioxidants that cannot be grouped as minerals or vitamins fall in the phytochemical category, including flavonoids. They are phenol compounds responsible for the coloration of plants, i.e., fruits and vegetables or seed leaves.

The most active in this group are catechins found in green tea and sesamol. The fat-soluble color of vegetables and fruits forms carotenoids. An example is beta-carotene, which is found in carrots in the body. It serves as a source of vitamin A in case of deficiency. Tomatoes have lycopene as an antioxidant, while dark green vegetables have zeaxanthin.

Secondary Antioxidants (peroxidase scavengers)

Unlike primary antioxidants, these function by reducing or decompressing hydroperoxides into stable compounds before transforming into active free radicals and stopping the chain reaction. The action can be combined with primary antioxidants for synergism and effective oxidative stress management. Examples include; Nordihydro garlic acid, tertiary butyl hydroquinone, butylated hydroxytoluene, propyl gallate, metal chelating agents, and butylated hydroxyanisole.

Sources of antioxidants.

The leading source of antioxidants is fruits and vegetables. Antioxidants are also available in nuts, grains, and animal proteins. Alpha-tocopherol is found in sunflowers, almonds, corn, broccoli nuts, and mangoes. Vitamin A-rich foods include liver, sweet potato, carrot, milk, egg yolk, and cheese. Ascorbic acid is found in most fruits and vegetables.

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Color-containing fruits and vegetables, especially oranges color, are rich in beta-carotene. Green vegetables have an abundance of lutein and zeaxanthin. Tomatoes and their products contain high levels of lycopene. Mineral antioxidants are provided as supplements or other available in plants and animals, for example, selenium (rice and wheat).

Properties of antioxidants

Antioxidants used mostly are phenol compounds, either monohydroxyl or polyhydroxy. Due to their low activation energy, they are not reduced (they would not donate hydrogen). As a result of this stabilization, it prevents the formation of other free radicals. A free radical chain reaction is minimized by donating hydrogen by the antioxidant. The intermediate antioxidant free radical does not oxidize due to its stability, thus preventing free radical chain reaction propagation. The resultant antioxidant radical can also react with lipid-free radicals, and a complex compound is formed, which is stable, thus preventing further damage by such radicals.

Examples of antioxidants

Vitamin E (tocopherol): this is a fat-soluble antioxidant. Among the eight members of this group, alpha-tocopherol is the most important. It is the most lipid-soluble and enhances the membranes' protection from lipid-related free radicals resulting from lipid peroxidation chain reaction. The intermediate of this reaction, oxidized alpha-tocopherol, can be recycled to its original form using other antioxidants, e.g., vitamins A and C.

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Vitamin C has reducing properties, can neutralize reactive oxygen species, and plays a vital role in cancer prevention. Its reaction with glutathione within the cell maintains it in a reduced state.

Glutathione is synthesized in the cells from amino acids. It can be maintained within the cell in either reduced or oxidized states mediated by enzymes such as glutathione reductases. It maintains the cell in its redox state, and due to its high concentration, it is the most vital cellular antioxidant. The cysteine group has reduction properties in its structure and can be oxidized reversibly.

Adverse effects of antioxidants

Toxicity in case of antioxidant overdose.
Reactive oxygen species (ROS) regulate cell adhesion, and their elimination compromises this.
ROS regulates the MAPK pathway for DNA repair. antioxidants actions will inhibit DNA repair and apoptosis
Immune system activation depends on ROS, and so does inflammatory response induction.
ROS plays a role in killing phagocytosed microbes by macrophages. Their elimination by antioxidants will impair this role.
Activation of the extracellular microbes depends on superoxide and nitric oxide, which eliminate antioxidants.

Conclusion

Contrary to what many people think about antioxidants, they’re, in fact, beneficial to a bodybuilder or any other fitness enthusiast during a steroid cycle. However, it would help if you regulated it to reap the full benefits.

Related Topics:Antioxidants Steroid Cycles

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Anabolic Steroids

Anavar Cycle for Men and Women

Published

5 days ago

April 22, 2024

SaneNt

Anavar (Oxandrolone) is a mild anabolic steroid often used for cutting purposes. We shall explore the Anavar cycle in this article.

Anavar Overview

Anavar (Oxandrolone) is an oral anabolic steroid initially developed in 1962 to promote lean muscle mass in individuals suffering from muscle-wasting conditions.

Its formulation aimed to create a mild drug with minimal side effects, making it safe for both women and children. Anavar was successfully used to treat catabolic illnesses, burns, infections, and post-surgery recovery. It also helped increase bone mineral density in osteoporosis patients.

Mechanism of Action

Mimics Testosterone: Anavar functions by mimicking the effects of testosterone, a hormone crucial for muscle growth and repair.

Anabolic Processes: It promotes anabolic processes in the body, aiding in protein synthesis—essential for muscle development and maintenance.

Nitrogen Retention: Anavar helps muscle cells retain more nitrogen, a building block of protein.

Increased Oxygenation: By increasing the number of red blood cells, Anavar enhances oxygenation of muscles, leading to improved strength and endurance.

Must Read: Top 10 Legal Steroids Products And Brands On The Market

1-8 Weeks Anavar Cycle

Let’s break down the Anavar cycle dosages for both men and women from week 1 to week 8:

Anavar Cycle for Men

- Week 1-2:
  - Start with 10mg per day.
- Week 3-4:
  - Increase to 20mg per day.
- Week 5-6:
  - Raise to 30mg per day.
- Week 7-8:
  - Maintain at 30-40mg per day.

Anavar Cycle for Women

- Week 1-2:
  - Begin with 2.5mg per day.
- Week 3-4:
  - Gradually increase to 5mg per day.
- Week 5-6:
  - Continue at 5-10mg per day.
- Week 7-8:
  - Maintain at 10mg per day.

Remember to monitor your progress, stay within safe limits, and consult a healthcare professional throughout your cycle. Safety first!

Tips to Optimize Results During Anavar Cycle

Optimizing your Anavar cycle involves strategic planning, adherence to best practices, and a focus on safety. Let’s explore key aspects to enhance your results:

Set Clear Goals
- Define your objectives: Are you aiming for fat loss, muscle gain, or strength improvement?
- Knowing your goals helps tailor your Anavar cycle accordingly.
Dosage and Duration
- Cycle Length: Anavar cycles typically last 5 to 8 weeks.
- Dosage: Start with a low dose (e.g., 10 mg/day for beginners) and gradually increase if needed.
- Split Doses: Divide daily dosage into 2 to 4 doses for consistent blood levels.
Diet and Nutrition
- Caloric Intake: Anavar is effective during cutting phases. Maintain a slight caloric deficit for fat loss.
- Protein: Consume adequate protein to support muscle preservation and growth.
- Healthy Fats: Include healthy fats for overall well-being.
Training Regimen
- Resistance Training: Focus on compound exercises (squats, deadlifts, bench press) to stimulate muscle growth.
- Progressive Overload: Gradually increase weights and intensity to challenge your muscles.
Cardiovascular Exercise
- HIIT (High-Intensity Interval Training): Incorporate HIIT sessions for fat burning.
- Steady-State Cardio: Longer sessions at moderate intensity can complement your routine.
Supplements
- Creatine: Enhances strength and performance.
- Fish Oil: Supports overall health and joint function.
- Multivitamins: Fill nutritional gaps.
Post-Cycle Therapy (PCT)
- Anavar is mild, but PCT helps restore natural testosterone production.
- Consider Clomid (Clomiphene) or Nolvadex (Tamoxifen) for PCT.
Monitor Side Effects
- Anavar has minimal side effects, but be vigilant.
- Liver Health: Use liver support supplements (e.g., milk thistle).
- Cholesterol: Monitor lipid levels.
Hydration and Rest
- Stay hydrated for optimal performance.
- Prioritize sleep and recovery.
Consult a Professional
- Always consult a healthcare provider or fitness expert before starting any cycle.
- Individualized advice ensures safety and effectiveness.

Anavar Cycle Stacking

Stacking Anavar with other steroids involves combining it with additional anabolic compounds to enhance overall results. Let’s explore the concept of stacking and some popular Anavar stacks.

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Anavar and Testosterone Stack

Purpose: This combination capitalizes on the well-tolerated nature of both steroids.

Benefits:

Muscle Gains: Users have reported 25–30 pounds of muscle gains when taken in moderate dosages.

Fat Loss: Testosterone speeds up subcutaneous fat loss.

Considerations:

Aromatization: Testosterone aromatizes, leading to temporary water weight gain.

Injection vs. Oral: Testosterone is injectable, while Anavar is oral.

Not Suitable for Women: Due to potential virilization effects.

Anavar and Winstrol Stack

For Men:

Lean Look: Anavar’s dry effect combines well with Winstrol’s hardness.

Strength and Vascularity: Users experience enhanced strength and vascularity.

For Women:

Lean Muscle: Anavar and Winstrol together promote lean muscle gains.

Caution: Monitor side effects carefully.

Anavar and Clenbuterol Stack:

For Men:

Fat Loss: Clenbuterol accelerates fat burning.

Anabolic Boost: Anavar complements Clenbuterol’s effects.

For Women:

Lean Physique: This stack helps achieve a lean, toned appearance.

Cautious Dosage: Start with low doses.

Anavar and Trenbolone Stack

Advanced Stack: Trenbolone is potent and not recommended for beginners.

Benefits:

Muscle Hardness: Trenbolone enhances muscle density.

Strength: Combined effects lead to significant strength gains.

Caution: Monitor side effects closely.

Anavar and Dianabol Stack

Purpose: Combining an oral steroid (Dianabol) with Anavar.

Benefits:

Synergy: Dianabol boosts initial gains, while Anavar maintains quality muscle.

Strength and Size: Users experience rapid strength and size improvements.

Considerations:

Liver Health: Both are hepatotoxic, so monitor liver function1.

Stacking should be done cautiously, considering individual goals, tolerance, and safety. Always consult a healthcare professional before combining any steroids.

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Top Anavar Benefits

Anavar (Oxandrolone) offers a range of benefits for both men and women in bodybuilding. Let’s explore them here.

Increased Lean Muscle Mass

Anavar helps build lean muscle tissue, contributing to a more defined physique.

Fat Loss

It promotes fat burning while preserving muscle, making it ideal for cutting phases.

Enhanced Strength

Users experience improved strength levels during workouts.

Minimal Water Retention

Unlike some steroids, Anavar doesn’t cause excessive water retention.

Improved Endurance

Anavar enhances stamina, allowing longer and more intense training sessions.

Vascularity

Users often notice increased vascularity and muscle pumps.

Safe for Women

Anavar is one of the few steroids safe for female use.

Positive Impact on Strength

Strongmen and powerlifters also benefit from Anavar.

Low Risk of Side Effects

Anavar is well-tolerated and doesn’t produce harsh effects.

Muscle Hardening

It contributes to a harder, more defined appearance.

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Preservation of Muscle During Caloric Deficits

Crucial for maintaining gains during cutting.

Improved Recovery

Anavar aids post-workout recovery.

Boosted Nitrogen Retention

Essential for muscle protein synthesis.

Enhanced Athletic Performance

Anavar helps athletes perform at their best.

Increased Metabolic Rate

Supports fat loss.

Positive Impact on Bone Density

Beneficial for overall health.

No Aromatization

Anavar doesn’t convert to estrogen.

Suitable for Older Adults

Helps combat muscle loss due to aging.

Minimal Androgenic Effects

Reduces risk of virilization in women.

Quality Gains

Anavar promotes high-quality muscle growth.

Potential Side Effects Associated With Anavar

Anavar (Oxandrolone), while considered relatively safe, does come with potential risks. Let’s explore these risks in detail:

Cholesterol

Anavar can impact cholesterol levels.

It may raise LDL (bad) cholesterol and lower HDL (good) cholesterol.

Regular monitoring is essential.

Liver Toxicity

Prolonged use of Anavar can harm the liver.

Liver enzymes may increase.

Avoid alcohol and other hepatotoxic substances.

Testosterone Suppression

Anavar can suppress natural testosterone production.

Post-cycle therapy (PCT) helps restore hormonal balance.

Excessive Pumps

Anavar can cause intense muscle pumps during workouts.

Manage this by adjusting training intensity.

Kidney Toxicity

High doses or prolonged use may harm the kidneys.

Stay hydrated and monitor kidney function.

Virilization (in Women)

While Anavar is safer for women, excessive dosages can lead to masculinization.

Watch for signs like deepening voice, facial hair growth, and clitoral enlargement.

Take Away

Obtaining genuine pharmaceutical-grade Anavar has become increasingly challenging through legitimate channels.

However, Anvarol from Etalaze.to or CrazyBulk provides impressive muscle benefits without the legal risks or health hazards associated with illegal products.

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Anavar, especially from Etalaze delivers steroid-like results safely, legally, and without requiring a prescription. Good luck in your next anavar cycle!

Bodybuilding Products

Telmisartan In Bodybuilding: An Expert’s Advice

Published

3 weeks ago

April 5, 2024

SaneNt

Telmisartan is a medication primarily used in medical circles to treat hypertension, also known as high blood pressure. It belongs to a class of drugs called angiotensin II receptor blockers (ARBs). The drug has piqued the interest of bodybuilders due to its potential benefits beyond blood pressure management.

Mechanism of Action

Telmisartan works by blocking the action of angiotensin II, a substance in the body that causes blood vessels to constrict, thereby reducing blood pressure. By blocking angiotensin II receptors, telmisartan dilates blood vessels, allowing blood to flow more smoothly.

Medical Application of Telmisartan

Treatment of Hypertension

Hypertension is a common medical condition characterized by elevated blood pressure levels. It is a significant risk factor for various cardiovascular diseases, including heart attack and stroke. The drug is prescribed to patients with hypertension to help lower their blood pressure and reduce the risk of associated complications.

Cardiovascular Protection

Telmisartan not only helps lower blood pressure but also provides cardiovascular protection. It has been shown to reduce the risk of heart attack, stroke, and other cardiovascular events in patients with hypertension or other cardiovascular risk factors.

Diabetic Nephropathy

In addition to treating hypertension, telmisartan is also used in the management of diabetic nephropathy, a type of kidney disease that occurs in people with diabetes. It helps slow down the progression of kidney damage in diabetic patients by reducing blood pressure and protecting the kidneys from further damage.

Heart Failure

Telmisartan may also be prescribed in the treatment of heart failure, a condition in which the heart is unable to pump blood effectively to meet the body's needs. It can help improve symptoms, reduce hospitalizations, and increase survival rates in patients with heart failure, particularly those who cannot tolerate other medications such as ACE inhibitors.

Combination Therapy

The drug is sometimes used in combination with other antihypertensive medications, such as diuretics or calcium channel blockers, to achieve better blood pressure control. Combination therapy is often recommended when blood pressure is difficult to control with a single medication alone.

Long-Lasting Effects

One notable feature of telmisartan is its long duration of action, with a half-life of around 24 hours. This means that it can be taken once daily, making it convenient for patients and potentially improving medication adherence.

Telmisartan Use In Bodybuilding

The use of Telmisartan within bodybuilding holds multifaceted advantages. Its diverse benefits offer significant potential for bodybuilders seeking enhanced performance.

Initially, the antihypertensive attributes of The drug serve as a vital adjunct in managing and preventing elevated blood pressure induced by AAS (Anabolic Androgenic Steroids). Additionally, Telmisartan exhibits efficacy in mitigating cardiac hypertrophy, particularly left ventricular hypertrophy, a prevalent concern among enhanced bodybuilders, which is often linked to premature mortality.

Moreover, Telmisartan's favorable impact on insulin sensitivity presents a counterbalance against the insulin resistance commonly associated with substances like MK-677, GH, and GH-releasing peptides.

Furthermore, Telmisartan demonstrates anti-inflammatory properties, facilitating a reduction in C-Reactive Protein levels, thereby addressing a significant factor in cardiovascular disease risk among bodybuilders.

Yet, the scope of Telmisartan's benefits extends further. By augmenting the activity of PPAR-delta, a protein integral to metabolic regulation and fat oxidation, Telmisartan potentially fosters fat loss and enhances body composition, offering an avenue for physique refinement in bodybuilding pursuits.

Here a few take aways on the application of the drug in bodybuilding:

Increased Endurance

Some users claim that Telmisartan enhances endurance levels.

Athletes may experience longer and more intense workout sessions without premature fatigue.

Improved Muscle Recovery

Telmisartan’s positive impact on blood flow may aid in post-workout muscle recovery.

It delivers essential nutrients and oxygen to muscles more efficiently.

Anti-Inflammatory Effects

The medication’s anti-inflammatory properties could reduce exercise-induced muscle soreness and inflammation.

Faster recovery between training sessions may be possible.

Fat Loss

Anecdotal reports suggest that Telmisartan may promote fat loss.

It could enhance the body’s ability to burn stored fat.

Muscle Hypertrophy

Some users speculate that Telmisartan might positively influence muscle growth.

This could be attributed to its impact on blood flow and nutrient delivery to muscle tissues.

Optimal Dosage for Bodybuilders

While Telmisartan is prescribed for specific medical conditions at varying dosages, the dosage used by bodybuilders may differ.

Scientific literature on Telmisartan’s direct impact on bodybuilding is limited.

Most information is based on user experiences and anecdotal evidence.

Generally, dosages for bodybuilders range from 20 to 80 milligrams (mg) per day, with some users dividing the daily intake into two doses.

Telmisartan Side Effects and Precautions

Telmisartan, like any medication, can have side effects and precautions that users should be aware of.

Side Effects

Dizziness or lightheadedness: The drug can cause dizziness or a feeling of faintness, especially when rising from a sitting or lying position.

Hypotension: Some individuals may experience a significant drop in blood pressure, leading to symptoms such as weakness, fatigue, or fainting.

Hyperkalemia: Telmisartan may lead to elevated levels of potassium in the blood, which can cause symptoms like muscle weakness, irregular heartbeat, or tingling sensations.

Fatigue: Feeling tired or lethargic is a common side effect of Telmisartan.

Headache: Some users may experience headaches as a side effect of the medication.

Diarrhea: Telmisartan can occasionally cause diarrhea or other gastrointestinal disturbances.

Back pain: Back pain has been reported as a side effect in some individuals taking Telmisartan.

Upper respiratory tract infection: Users may experience symptoms of a cold or flu-like illness.

Sinusitis: Inflammation of the sinuses may occur in some individuals.

Muscle cramps: Telmisartan can sometimes cause muscle cramps or spasms.

Allergic reactions: Rarely, individuals may experience allergic reactions such as rash, itching, swelling, or difficulty breathing.

Precautions

Pregnancy: Telmisartan should not be used during pregnancy due to the risk of harm to the fetus.

Breastfeeding: It is not recommended to use Telmisartan while breastfeeding, as it may pass into breast milk and harm the nursing infant.

Kidney disease: Caution should be exercised in individuals with kidney disease, as Telmisartan can affect kidney function.

Liver disease: Patients with liver impairment may require dose adjustments or close monitoring while taking Telmisartan.

Heart conditions: Individuals with heart disease, heart failure, or a history of heart attacks should use Telmisartan with caution under the supervision of a healthcare professional.

Diabetes: Telmisartan may affect blood sugar levels, requiring adjustments in diabetes medications.

Salt/volume depletion: Telmisartan may cause excessive lowering of blood pressure in individuals with salt or volume depletion.

Hyperkalemia: Patients with conditions predisposing them to hyperkalemia should be closely monitored while taking Telmisartan.

Renal artery stenosis: Telmisartan may exacerbate renal artery stenosis, a narrowing of the arteries that supply blood to the kidneys.

Dual blockade of the renin-angiotensin system: Concurrent use of Telmisartan with other medications that affect the renin-angiotensin system may increase the risk of hypotension, hyperkalemia, and renal impairment.

Driving and operating machinery: The drug may cause dizziness or fatigue, which can impair the ability to drive or operate machinery.

Where to Buy Telmisartan Online

Telmisartan is available through various channels. Here are some options for obtaining Telmisartan:

Local Pharmacies

You can visit local pharmacies such as Walgreens, CVS Pharmacy, Walmart, Harris Teeter, or Target (CVS). Prices may vary, but the drug typically starts at $10.751.

Some pharmacies offer home delivery services, allowing you to order online and have the medication delivered to your doorstep.

Online Prescription Services

Sesame: You can book a same-day video appointment with a healthcare provider on Sesame. They can write a prescription for Telmisartan, and you can pick it up at a local pharmacy.

Push Health: While Telmisartan is a prescription medication, you can consult with a medical provider online through Push Health to obtain a prescription.

Related Article: 6 Best Ways to Verify If a Steroid is Fake

Online Pharmacies

BuyMicardPl: This online platform offers Telmisartan (generic Micardis) without a prescription4.

PharmacyPortal: Check their catalog for Telmisartan availability.

Always consult with a healthcare professional before starting any new medication, especially if you have specific health conditions or are taking other medications. They can guide you on the appropriate dosage and monitor your progress.

Telmisartan Alternatives

While The drug has gained attention among bodybuilders, it’s essential to explore alternative options. Here are some medications that may have similar effects or benefits:

Lisinopril (Prinivil, Zestril)

An angiotensin-converting enzyme (ACE) inhibitor, lisinopril helps lower blood pressure and may have a calming effect on nerves and the heart12. It’s commonly used for hypertension.

Losartan (Cozaar)

Another angiotensin II receptor blocker (ARB) like Telmisartan, losartan can help manage blood pressure and has potential benefits beyond that3.

Olmesartan (Benicar)

Also an ARB, olmesartan is used for hypertension and may have similar effects on blood flow and muscle recovery4.

Valsartan (Diovan)

Yet another ARB, valsartan is prescribed for high blood pressure and could be considered as an alternative4.

Metoprolol (Lopressor)

A beta-blocker, metoprolol can reduce heart rate and blood pressure. It’s sometimes used off-label for social anxiety and movement disorders52.

Propranolol (Inderal)

Another beta-blocker, propranolol may help with anxiety and tremors. It’s used in various contexts, including performance anxiety5.

Candesartan

An ARB similar to Telmisartan, candesartan may have comparable effects on blood pressure and muscle function.

Irbesartan

Yet another ARB, irbesartan could be considered as an alternative for bodybuilders.

Fosinopril

An ACE inhibitor, fosinopril might have similar effects on blood pressure and overall health.

Nebivolol

A unique beta-blocker with vasodilating properties, nebivolol could be explored as an alternative2.

Overall

In conclusion, while some individuals may speculate about the potential benefits of Telmisartan in bodybuilding due to its purported effects on blood pressure regulation and muscle function, it's essential to emphasize that using Telmisartan for bodybuilding purposes is not medically advised or supported.

Telmisartan is a medication prescribed for managing high blood pressure and reducing the risk of cardiovascular events, and its off-label use for bodybuilding carries significant risks and potential side effects. Engaging in such usage without medical supervision can lead to adverse health outcomes and complications.

Therefore, individuals interested in bodybuilding should prioritize safe and evidence-based approaches, consulting with healthcare professionals and adhering to established guidelines for training, nutrition, and supplementation.

Must Read: Tren Cycle for Beginners

Bodybuilding

Is My Gear Bunk? How to Deal With Underwhelming Results

Published

1 month ago

March 24, 2024

SaneNt

The concern about whether one’s gear is “bunk” or ineffective is indeed a common one in bodybuilding forums. When results don’t meet expectations, it’s natural to question the quality of the supplements or steroids being used.

Training and Diet

Are the training regimen and diet optimized for the goals? Consistency and intensity in workouts, along with a diet rich in protein and other nutrients, are crucial for muscle gains.

Rest and Recovery

Muscles need time to repair and grow after workouts. Adequate sleep and rest days are essential.

Realistic Expectations

It’s important to set achievable goals. Unrealistic expectations can lead to disappointment, regardless of the gear’s quality.

Proper Dosage and Cycle

Ensuring that the gear is used in the correct dosage and cycle length is important for effectiveness.

Metrics for Evaluation

Are the right metrics being used to assess progress? Muscle gains can be slow and incremental, and focusing solely on the scale might not reflect true progress.

Quality and Authenticity

Finally, if all other factors are in place, it might be worth verifying the authenticity and quality of the gear.

PEDs Awareness

Understanding the types of PEDs, their effects, and the risks involved is crucial. PEDs can range from anabolic steroids to hormone supplements like HGH1.

Injectable Hormones

Injectable hormones such as testosterone and human growth hormone (HGH) are commonly used in bodybuilding. They can lead to significant muscle growth but also come with risks such as hormonal imbalances and organ damage23.

Steroid Doses

The dosage of steroids must be carefully managed. Excessive doses can lead to severe side effects, while too little may not provide the desired muscle growth4.

Cycle Length

The duration of a steroid cycle should be planned according to individual goals and the body’s response to the steroids.

Also See: Top 10 best Immune Boosting Supplements to buy in 2024

Post-Cycle Therapy (PCT)

After a steroid cycle, PCT is essential to help the body recover and maintain the gains made.

Legal Implications

The legality of steroid use varies by country, and it’s important to be aware of the laws to avoid legal repercussions.

Ethical Considerations

The use of PEDs raises ethical questions about fairness in competition and the integrity of the sport.

Health Monitoring

Regular health check-ups are necessary to monitor the effects of PEDs on the body.

Mental Health

The psychological impact of PEDs, including dependency and body image issues, should not be overlooked.

Nutritional Support

A diet that supports the increased metabolic demands of bodybuilding and PED use is vital.

Supplement Quality

Ensuring the quality and purity of PEDs and supplements is important to avoid contaminants that could cause harm.

Training Adaptation

The training regimen may need to be adjusted when using PEDs to optimize results and minimize injuries.

Peer Influence

Be cautious of advice from fellow athletes or online forums; not all sources are reliable or have your best interests in mind.

Long-Term Consequences

Consider the potential long-term health consequences of PED use, which can include cardiovascular issues, infertility, and other endocrine disorders.

Metrics to Evaluate These Parameters

Evaluating the legitimacy and effectiveness of bodybuilding gear involves a multifaceted approach. Here are metrics that can be used to measure each of the 20 parameters above.

Training and Diet

Track workout progress, dietary adherence, and macronutrient intake.

Rest and Recovery

Monitor sleep quality and quantity, as well as muscle soreness and recovery rate.

Realistic Expectations

Set and review short-term and long-term bodybuilding goals.

Proper Dosage and Cycle

Log dosages and cycle lengths, and compare them with recommended guidelines.

Metrics for Evaluation

Use body composition analysis, such as DEXA scans or calipers, to measure fat and muscle changes.

Quality and Authenticity

Verify product labels and third-party testing for substance authenticity.

PEDs Awareness

Educate oneself on PED types and effects through credible sources.

Injectable Hormones

Blood tests to monitor hormone levels and ensure they are within safe ranges.

Steroid Doses

Record and adjust dosages based on physiological responses and side effects.

Cycle Length

Plan and document cycle durations, noting any physiological changes.

Post-Cycle Therapy (PCT)

Assess hormonal balance and recovery post-cycle with blood tests.

Legal Implications

Stay informed about local laws regarding PED use.

Ethical Considerations

Reflect on personal ethics and the impact of PED use on competitive fairness.

Health Monitoring

Regular health screenings, including liver and kidney function tests.

Mental Health

Self-assessments or professional evaluations for mental well-being.

Nutritional Support

Nutritional logs and periodic reviews with a dietitian.

Supplement Quality

Check for certifications like NSF or Informed-Choice on supplements.

Training Adaptation

Adjust training programs based on performance metrics and recovery.

Peer Influence

Critically evaluate advice from peers against scientific evidence.

Long-Term Consequences

Longitudinal health tracking to identify potential delayed effects of PED use.

Optimizing Calorie Intake: A Key Strategy to Manage Weight Effectively

When it comes to bodybuilding, one of the crucial factors that can significantly impact your progress is your calorie intake. Whether you are looking to build muscle mass, lose fat, or maintain your current weight, understanding and optimizing your calorie consumption is essential. In this article, we will explore the recommended calorie intake for bodybuilders and how it can help mitigate abnormal weight fluctuations.

Why Calorie Intake Matters for Bodybuilders

Calories are units of energy that our bodies need to function properly. For bodybuilders, caloric intake plays a vital role in achieving their fitness goals. Consuming the right amount of calories ensures that you have enough energy for workouts, muscle recovery, and overall performance.

Determining Your Calorie Needs

The recommended daily calorie intake for bodybuilders varies depending on various factors such as age, gender, weight, height, activity level, and fitness goals. To determine your specific calorie needs accurately, consider using online calculators or consulting with a nutritionist or dietitian.

Recommended Calorie Intake for Bodybuilders

As a general guideline, bodybuilders aiming to build muscle mass often follow a caloric surplus diet where they consume more calories than they burn. This surplus provides the extra energy needed for muscle growth and repair. On the other hand, those looking to lose fat may opt for a caloric deficit diet where they consume fewer calories than they burn to promote fat loss while preserving muscle mass.

Mitigating Abnormal Weight Fluctuations

To mitigate abnormal weight fluctuations as a bodybuilder, it is crucial to monitor your calorie intake consistently and adjust it based on your progress and goals. Rapid changes in weight can indicate an imbalance between calorie consumption and expenditure.

Incorporating Nutrient-Dense Foods

Apart from monitoring calorie intake, focusing on nutrient-dense foods is essential for overall health and optimal performance. Include a variety of protein sources, complex carbohydrates, healthy fats, fruits, and vegetables in your diet to ensure you meet all your nutritional requirements.

Must Read: What Anabolic Steroids Can Be Used for Joint or Ligament Injuries

Top Legit Steroid Pharmaceuticals for Bodybuilders: Where to Find Effective Gear

When it comes to bodybuilding, finding legitimate steroid pharmaceuticals that provide effective gear is crucial for achieving desired results safely and efficiently. Not all suppliers can be trusted, so it's important for bodybuilders to do their research and only purchase from reputable sources. Here are some top pharmaceutical companies known for selling high-quality, effective gear.

1. Alpha Pharma Gear Suppliers

One of the top pharmaceuticals globally, Alpha Pharma is a well-known pharmaceutical company that offers a range of steroids specifically designed for bodybuilding purposes. They are known for their quality products and have gained trust among many bodybuilders worldwide.

2. Dragon Pharma

Dragon Pharma is another popular choice among bodybuilders looking for reliable steroid products. They are known for their commitment to quality and effectiveness in helping athletes achieve their fitness goals.

3. Balkan Pharmaceuticals

It is a trusted name in the world of bodybuilding supplements, offering a variety of steroids that are known for their potency and reliability.

4. Kalpa Pharmaceuticals

This outlet is recognized for its high-quality gear that caters to the needs of bodybuilders seeking safe and effective performance-enhancing drugs.

5. Geneza Pharmaceuticals

Geneza is a reputable supplier of steroids that are widely used by bodybuilders due to their effectiveness and quality standards.When purchasing steroids from pharmaceutical companies, it's essential to ensure they are legit and follow proper guidelines for safety and authenticity. Always verify the credentials of the supplier before making a purchase, prioritize quality over price, and consult with healthcare professionals if needed.

Bonus: Etalaze Shops - Your Ultimate Online Gear Store

Looking to elevate your bodybuilding game with top-notch supplements and legit steroids? Look no further than Etalaze shop - the ultimate destination for bodybuilders seeking high-quality products at competitive prices.

At Etalaze, you'll find a wide range of legal steroids and human growth hormones to help you achieve your fitness goals effectively. With discounts and deals regularly offered, shopping online at Etalaze ensures convenience and affordability without compromising on product quality.

Whether you're a seasoned bodybuilder or just starting out on your fitness journey, Etalaze has the products to support your needs. From muscle building to cutting cycles, their selection caters to various preferences and requirements, making it a one-stop shop for all your supplement needs.

Don't settle for anything less than the best when it comes to enhancing your performance and physique. Choose Etalaze as your go-to store for legal steroids and experience the difference in quality and results that set them apart as the ultimate destination for bodybuilders worldwide.

Overall

In conclusion, navigating the world of cycles and PEDs in bodybuilding can be fraught with uncertainties. While concerns about the quality and effectiveness of gear are valid, it's crucial for pro bodybuilders to approach the situation with a combination of skepticism and proactive measures. By educating themselves on authentication methods, seeking reputable sources for gear, and prioritizing holistic approaches to training and nutrition, athletes can better manage the risks associated with potentially bunk gear.

Ultimately, by focusing on consistency, dedication, and a commitment to your cycling needs, one can overcome the setbacks we've discussed and strive for success, regardless of the challenges you may face along the way. Good luck in your cycling journey!

Related Article: The Ultimate Guide to Safe Steroid Injection